The Doom Patrol tries to restore the memories and abilities of Flex Mentallo, while Rita confronts her self-doubt and Larry realizes how tied he is to the Negative Spirit.

The Doom Patrol (along with Niles & his daughter) are still mini-sized after their last adventure. Ultimately, Niles will have to sacrifice something precious to save the team.

Cliff, Jane, and Rita pursue a time-altering doctor in their reluctant quest to help Niles and Dorothy. Meanwhile, Vic meets a military vet who challenges his beliefs.

Niles, Rita, and Larry end up in the interdimensional clutches of Red Jack, an infamous villain who feeds on pain, while Cliff visits his daughter with Jane.