Hirasaka Ryuji, who has begun working at the gynecology department of St. Juliana Hospital, is surprised to find out that the head of the department is Jinguji Narumi, a woman he once raped as an experimental subject. Rather than seeking revenge on Ryuji, Narumi asks him to train nurses for the "special ward." Their mission is to train and raise sex slaves to serve wealthy, socially prominent male patients. The first candidate nurse is Nanase Ren. Ryuji finds Ren's "weak point" and uses it to violently and lasciviously take Ren's virginity. Ryuji attacks erogenous zones that Ren didn't even know she had, and she writhes in agony/ecstasy... The humiliation and dark pleasure! The pure angel in a white coat changes into something bewitching and lascivious...

Hirasaka Ryuji's second candidate is Shinjo Reimi, the head nurse of the gynecology department. Reimi is proud and takes great pride in her work, and she berates Ryuji for being careless and sloppy. Humiliated, Ryuji finds Reimi's "weak point" and slowly trains her.

Hirasaka Ryuji has successfully trained two nurses, Nanase Ren and Shinjo Reimi, into sex slaves. However, he has found a new candidate nurse for the "special ward", Fujisawa Ako, who works at a pharmacy. Ako is an excellent subject, but her fear of men keeps Ryuji away, and he is initially unable to find her "weak point." However, Ryuji accidentally eavesdrops on Ako's phone call and learns her secret. "Well, I'll teach you about the world, men, and the real you, Miss Ako of Fujisawa Pharmaceuticals." In Ryuji's cunning scheme Ako is framed for stealing a new drug, and now she is helpless and broken, engulfed in a whirlpool of perverse pleasure. Another pure angel is degraded.

Gynecologist Hirasaka Ryuji continues his training, known as the Withering Experiment, designed to turn nurses at St. Juliana Hospital into sex slaves for the "special ward" where they will serve wealthy male patients. Now his tentacles reach out to the last candidate, Kodama Hikaru. Ryuji has a hard time dealing with Hikaru's wild behavior, but when he discovers that her "weak point" is a family member's illness, he uses this as an excuse to bind her hands and feet and begin his experiments. Through the intense and lewd experiments, Hikaru's hidden pleasures are forcibly awakened. Though terrified by the horrible pleasure, her young body gradually begins to bloom in a mysterious and lewd way...

"Service nurses" - it's my job to raise them. On the surface they appear innocent and carefree, but underneath they're all slutty pigs! I've taught them the joys of being a woman. Soon all their training will be over, and they'll be complete sex slaves. Koi, Reimi, Ako, Hikaru, and that guy too... And here I will see the pinnacle of sex slavery. Will their various intersecting desires lead to heaven? Or hell? They all have one thought...