After a car crashes into Joe’s Bar, Andy and Sullivan lead the team of firefighters as they work to rescue their fellow crewmates Ben and Pruitt, Grey Sloan doctors and interns, and bar patrons before the building comes crumbling down.

The crossover continues on Grey's Anatomy S16E10 Help Me Through the Night (II).

Andy takes the day off to continue to sort out her family life; Maya and Carina do their best to maintain their relationship while unable to physically see each other due to COVID-19 restrictions, and Sullivan strives to work on his sobriety. Meanwhile, the team responds to a call involving a wild animal.

Andy deals with the aftermath of a trauma.

A shoddily assembled structure poses a dangerous challenge for our heroes leaving Ben with a difficult choice to make. Maya and Carina work to get their relationship back on track, while Natasha must decide what – or whom – she wants to prioritize.