With the absence of Captain Pruitt, Andy and Jack try to navigate how to work together, and a car accident on a rural road puts both the victims and the crew’s lives at risk.

A blackout in Seattle creates dangerous situations throughout the city and the members of Station 19 head out on calls, including locating a missing girl and helping a man on life support where every second counts.

After some tense and traumatic experiences, the firefighters get a visit from a psychologist .

Andy returns to work while she and Jack fight to save people trapped in a collapsing bowling alley. Meanwhile, Ben confronts Sullivan about his drug problem; and Maya’s mother, Katherine, pays Maya a visit.

When the COVID-19 pandemic hits Seattle, the Station 19 crew leans on each other for support. Andy tries to make sense of her mother’s return, while Sullivan settles into a new routine. And it’s all-hands-on-deck when a group of teenagers unintentionally starts a wild fire.

Andy takes the day off to continue to sort out her family life; Maya and Carina do their best to maintain their relationship while unable to physically see each other due to COVID-19 restrictions, and Sullivan strives to work on his sobriety. Meanwhile, the team responds to a call involving a wild animal.

Andy and Sullivan find a way to stay connected; Ben confronts a tough loss, and Jack and Inara grow closer. Meanwhile, while off duty, the crew jumps into action to help a mother in distress, but their heroic efforts spark conflict with police officers who are less than eager to offer support.

In the wake of national outcry after the tragic murder of an unarmed Black man, Maya brings in Dr. Diane Lewis to grief counsel the team.

Andy tracks down a witness to testify at her trial. Meanwhile, Carina and Maya deal with a stressful situation, and the crew responds to a car wreck.