The Station 19 crew responds to a drunk driver scene. Meanwhile, Dean receives advice from Pruitt on a difficult situation, and Sullivan seeks help from Dr. Amelia Shepherd.

Andy becomes painfully suspicious of the circumstances surrounding her mother’s death and goes to her aunt looking for answers. Meanwhile, the members of the crew work to evacuate a doctor from Pac-North hospital and find themselves in a life-threatening situation; and Sullivan undergoes surgery for his chronic leg pain.

Andy takes the day off to continue to sort out her family life; Maya and Carina do their best to maintain their relationship while unable to physically see each other due to COVID-19 restrictions, and Sullivan strives to work on his sobriety. Meanwhile, the team responds to a call involving a wild animal.

After a terrifying lightning strike, the Station 19 crew works overtime to extinguish the fire at Meredith Grey's home. Meanwhile, Maya is rushed to Grey Sloan Memorial Hospital due to a medical emergency.

Andy steps into the station’s captaincy as Jack's life hangs in the balance. The team is called to a hostage situation. Natasha fights for her career, and Maya and Carina make a choice.