Michael begins his American odyssey in New York City. Starting at Grand Central Terminal, the 'gateway to the nation', he boards the Manhattan subway system, the busiest rail transit system in the US. His first stop is the Rockefeller Centre, where he gets a bird's eye view of Manhattan Island and learns how about the technology which enabled the city to build up. Portillo heads to the Financial District, where, over a Lobster Newberg, he finds out how the dodgy political dealings of the era's famous industrialists earned them the nickname 'Robber Barons'. He observes their better side at the Metropolitan Museum of Art as he learns that philanthropy helped the city's burgeoning art scene, before finishing his journey midtown, among the bright lights of Broadway.

Michael continues his American journey in Manhattan's Lower East Side, where he narrowly avoids a scrap with an historic gang of New York and visits the grim tenement buildings where thousands of the city's immigrants lived and worked. In the West Side, Michael discovers how a once lethal run of track has been transformed into a public park, raised above the city streets. Forsaking the rails for a ferry, Michael heads for Ellis Island, where some 12 million immigrants entered America. Michael is given a privileged tour of the gleaming new transport hub under construction close to the site of Ground Zero.

From Manhattan, Michael follows his Appleton's Guide east, travelling on the Long Island Railroad. He begins in Brooklyn, where he learns the incredible story behind the world's first steel suspension bridge. Divided by a common language, Michael struggles to order a pizza before continuing to Queens and the site of an ambitious engineering project that will transform New York City's rail network. Moving east through Long Island, he visits one of the country's most decadent mansions, owned by an oil tycoon known as Mr Monopoly, where he gets into a flap dancing the Charleston, before ending his journey on Long Island's eastern most tip at New York's first lighthouse.

Michael follows America's mighty Hudson River north, riding on the United States' national rail carrier service, Amtrak. He learns from Amtrak's police chief about some of the nation's most infamous train robbers, then upriver at Tarrytown, he is spooked by the stories of one of America's greatest writers, Washington Irving, author of Sleepy Hollow. On the east bank of the Hudson, he stops at Garrison, site of many guerrilla battles during the Wars of Independence, where he hears about the greatest turncoat in American history and learns about the many famous military leaders who trained at West Point.

Michael Portillo continues his railroad journey through New York State following his Appleton's Guide. Beginning in the city of Poughkeepsie, he visits a famous all-female university, alma mater of Jane Fonda and Meryl Streep. He discovers the tumultuous history of the Poughkeepsie-Highland Railroad Bridge and follows the train line up to the Catskill Mountains, admiring its picturesque scenery from an altogether different type of line - a zip wire. Back on safe ground, he discovers that the dramatic landscape inspired artists of the Hudson River School. Arriving in New York's state capital, Albany, he samples a drop of Albany Ale before rubbing shoulders with the State Senator.

Michael heads west through New York State. He has a lightbulb moment in Schenectady, when he discovers how Thomas Edison's General Electric Company also leads the way in modern rail technology. In Utica, he investigates Lock 20 of 57 along the early 19th-century Erie Canal - 325 miles of waterway which connected the Great Lakes with the Atlantic Coast via the Hudson River. A yellow brick road beckons Michael to Chittenango, where a Kansas farm girl introduces him to a lion, and a tin man. On a hillside near Palmyra, Michael finds out about a farm boy, Joseph Smith, and his Book of Mormon, from one of the 15 million believers who follow his religion today. Further west in Rochester, Michael discovers the story behind another famous 19th-century name still trading today: George Eastman, who launched mass market photography with his Eastman Kodak company.

Michael braves the awesome power and drenching spray of Niagara Falls on the Maid of the Mist to share what artists, daredevils and millions of tourists have billed as one of the most spectacular experiences on the planet. Reaching Buffalo, he lunches on the city's famous Buffalo wings and discovers it was once the centre of the world's grain trade. Touring Silo City, Michael learns about the invention which propelled the port of Buffalo into its dominant position - the grain elevator - and how the railroads sealed the deal. Awe-inspiring engineering is revealed at the 12-acre Colonel Ward water-pumping station, the largest construction ever built on the Great Lakes, and capable of delivering 30 million gallons of water per day to the city of Buffalo.