In 1997, Detective Russell Poole launches the first major investigation into the murder of the Notorious B.I.G. Ten years later, Detective Greg Kading is asked to re-open the still-unsolved case.

Kading and Dupree brief the Biggie Smalls Task Force on the case's popular theories. Poole and Miller travel to Las Vegas to investigate a possible connection between Biggie and Tupac's murders.