When an accident brings a familiar patient into the Chastain ER, the doctors must face the reality of figuring out how to proceed with the best care, which leads the whole staff questioning every decision. Meanwhile, The Raptor and Leela deal with a patient returning with the long-term effects of COVID.

When the first day of Kit's experimental Flight Go team program sends Conrad out into the field, he builds a new relationship with a fellow doctor along for the ride. Devon works with Trevor for the first time on a patient with a mysterious fever, the cause of which can't be found. Meanwhile, Bell is hiding a secret from the whole staff and they are starting to become suspicious.