Bell's confidence in Quovadis continues to waver when the poster child for one of its medical devices, Henry Barnett, is rushed back into the ER, experiencing seizure-like symptoms. Meanwhile, Mina's past comes to light when her mother, famous Nigerian surgeon Dr. Okeke, pays a visit to Chastain, and Conrad makes a risky move when Henry returns to the hospital.

Intending to garner publicity for the hospital, Cain tries to recruit Bell and Kit on a dangerous surgery. The Raptor develops an emotional attachment to a patient. Mina's friend arrives with shocking news.

After a plane crashes in Atlanta, Devon is overcome by guilt at the thought that he could have prevented it. Adaku returns to ask Mina a big favor. Conrad and Nic consider risking it all to investigate a drug that might be linked to Jessie's death.

Conrad comes under fire when a former patient files a malpractice lawsuit against him, putting Bell in a difficult position with Red Rock. The doctors perform a risky brain surgery. Mina discovers that Adaku has a dangerous heart condition.

Devon and Conrad face a moral dilemma over a suicidal patient who is in need of a liver transplant.

Nic and Mina treat a patient battling a failing heart VAD, forcing them to find a new battery to save her life. Conrad gets a call from a patient who is in crisis. Cain tries to get close to Bell's business partner from the supplement company.

Conrad meets with a high-profile soccer player suffering from mysterious symptoms. Nic springs into action when she notices Kyle falling into a deep depression and fears he could be suicidal. Devon butts heads with Irving over patient space.