Conrad receives the call he's been waiting for when a heart becomes available for a patient who has been on the transplant list for two years. But when a congressman is admitted to the hospital after a heart attack, he is prioritized and derails Conrad's patient's surgery. Meanwhile, Nic grows suspicious of one of the doctors after a file goes missing, Dr. Bell tries to manipulate Mina and Devon is put to the test when a patient's condition requires a split-second decision.

An old army buddy and fellow surgeon visits Conrad at the hospital. Meanwhile, the team is put to the test when they have to save the life of an uninsured and undocumented patient, while simultaneously battling the hospital's administrators, who fear the patient will cost millions. Also, Dr. Bell experiments with a new medication for his tremor and Nic swears to investigate the mystery surrounding missing medical records.

Conrad is hit by a bike and badly sprains his ankle, but works through it when he takes the case of his old medical professor, who is hallucinating visions of her old patients. Devon is tasked with admitting Conrad, who refuses any sort of treatment. Nic tries to navigate her emotions while mourning the loss of a patient and Bell operates on a foreign dignitary with unforeseen complications. Meanwhile, Lane and Bell's relationship grows closer.

In a final and drastic attempt to save Nic from Lane's acts of sabotage, Conrad must call in a favor from the one person he promised he never would. Meanwhile, Mina's partnership with The Raptor takes on new colors when Micah is rushed back to Chastain with major heart complications and Dr. Bell's alliance with Lane is put to the ultimate test when one of her patients is readmitted.