The SWAT team discovers a new version of PCP with ties to an escaped drug dealer who created a version that ravaged the city decades earlier. Tan’s personal ties to the case emerge when he brings in his mentor, Ben Mosley, the former lead detective on the original drug case, to help. Also, Chris weighs a major decision regarding her romantic relationship with Kira and Ty, and Hondo’s patience is tested by his new familial responsibilities.

The SWAT team must protect a hotel full of civilians after a joint task force mission with the LAPD Gang Division goes wrong, and the city’s most dangerous gang leaders scatter across the building to find an escape. Also, Luca’s efforts to coordinate the team’s mission are complicated when his brother, Terry, a freelance stringer reporter, crosses police lines to shoot footage.