9-year-old Sheldon Cooper is a once-in-a-generation mind capable of advanced mathematics and science but learns that isn’t always helpful growing up in East Texas, a land where church and football are king.

To appease his worried mother, Sheldon employs the techniques of a self-help book to try and make a friend.

George Sr. strikes a deal with Sheldon to tutor Georgie when poor grades threaten to keep him from playing football

When Sheldon moves to Dallas to attend a school for gifted children, the family struggles to cope with his absence.

When Sheldon is no longer academically challenged at Medford High, he audits a college class taught by Dr. John Sturgis.

When George Sr. asks Sheldon to keep a secret from Mary, the stress of not being honest drives Sheldon to hideout at Tam’s for his first sleepover.

When Sheldon has to spend a few days in the hospital, he turns into the world’s worst patient. Also, Missy gets a taste of what life would be like without her twin.

Sheldon and Dr. Sturgis have their first fight when Dr. Sturgis marks a question wrong on Sheldon's test. Also, Mary takes over for Pastor Jeff when he's out sick.

Sheldon moves in with Dr. Sturgis for the weekend to see what his life will be like in college. Also, a lonely Mary tries to bond with the other Coopers during Sheldon's absence.

The Coopers help Pastor Jeff through a rough patch in his marriage. Also, Sheldon pressures church members for donations when Mary takes him to work for a day.

Without Dr. Sturgis’ university class, Sheldon must find a new way to stay academically challenged. Also, Mary helps Pastor Jeff avoid temptation with his girlfriend.

The University makes George Sr. a lucrative job offer in the hopes of recruiting Sheldon. Also, Georgie gets a job working for Connie's new boyfriend, and Mary is determined to rid her home of greed.

Sheldon fakes being sick to avoid a swim test at school. Also, Dr. Sturgis spies on Connie's new boyfriend.

When Sheldon learns the house next door is for sale, he takes it upon himself to find the perfect neighbors. Missy is torn when she’s forced to pitch against her boyfriend at the baseball game.

Sheldon discovers that Mary's been keeping a secret about his future. Also, Connie is furious when she learns Dale fired Georgie.

After graduating high school, Sheldon has a breakdown when he realizes he may not be ready for college. Dale tries to make amends with Connie.