一位患有自闭症的年轻外科医生为了完成他的培训搬到加州，他凭借自己高超的技术打消了同事们的质疑。

在圣博纳旺蒂尔医院，肖恩自闭症带来的偏见迫使他只能做些无关紧要的杂务，而同事们却毫不犹豫地对他的诊断给予了肯定。

肖恩和克莱尔临时需要保留肝脏准备进行移植手术，马库斯被迫与尼尔合作，为一个富有的病人做常规手术。

尼尔冒险救了一位母亲和她未出生的孩子，使医院面临法律问题。肖恩和克莱尔治疗一个成人电影明星。

肖恩怀疑一个男孩被误诊为癌症。一位病人的过敏反应暴露了他与儿子之间的长期不和。

肖恩和克莱尔制定了能够挽救年轻新郎的腿和生命的手术计划，但病人的亲人必须学会配合治疗。

肖恩接手治疗一个自闭症患者，而一个意想不到的人对他抱有偏见。贾里德直面自己作为外科医生的局限性。

肖恩在一场抢劫事件中的反应造成了生命危险。与此同时，在肖恩痛苦的一天过后，亚伦担心自己对他的帮助不够多。

尼尔因挽救一个重病男孩的生命而感到压力重重。缺失的组织样本可能会让一位母亲面临不必要的手术。

一名新来的医生一开始展现出迷人的魅力，而后却让手术团队陷入尴尬境地。肖恩和尼尔治疗一位职业玩家。

马库斯请尼尔在一对双胞胎之间进行有难度的肾脏移植手术。与此同时，肖恩开始因工作中的压力而感到不堪重负。

双胞胎在手术后出现了并发症，迫使团队做出改变人生的决定。肖恩宣布了一个出人意料的消息。

肖恩怀疑他的病人对她受伤的原因撒了谎。与此同时，尼尔的个人生活可能会危及他病人的生命。

肖恩和贾里德争论该如何治疗一名儿童的癌症，而克莱尔和一位争强好胜的新住院医生需要共同努力，拯救一位感染了超级病菌的单身父亲。

肖恩和摩根在修复一名少女心脏缺陷的手术方面产生分歧。一名新住院医生怀疑一名囚犯捐献器官的动机。

一名瘫痪男子腿上的意外知觉让尼尔觉得他或许可以重新走路。马库斯需要补救一次失败的整容手术。

一位病人使用被盗的保险卡，克莱尔和摩根在如何应对此事上意见不一。肖恩与一名准备接受手术的青少年患者建立了联系。

肖恩得知了关于亚伦健康状况的令人不安的消息。团队试图揭开一个大学生受伤的真相。

肖恩提议对一名无家可归的病人进行治疗，这使他和贾里德成为马库斯的攻击对象。克莱尔决定进行一项有风险的心脏手术。

肖恩反对尼尔，奥德瑞冒着诉讼的风险，而亚伦不在乎选择哪位外科医生给自己做手术。

克莱尔为了住院医生工作时间的问题与马库斯对质，同时与尼尔一起诊治一位患有不孕症的病人。肖恩发誓要帮助亚伦康复。

肖恩以他过去的经历来帮助一名少年。克莱尔介入受伤的攀岩者和她的父母之间。亚伦直面个人悲剧。

一名患者请肖恩和阿历克斯对他的丈夫保守秘密。一名女子需要做心脏手术，但克莱尔和尼尔在治疗方案上产生了分歧。

一名音乐会小提琴手的手指被感染，肖恩和摩根在问题的严重性方面意见不一。克莱尔与一位有着神秘问题的年轻患者成为朋友。

克莱尔努力减轻一位垂死的大学同学的痛苦。两个固执的兄弟之间将要进行器官移植，肖恩和摩根协商条件。

一位病人被迫向丈夫透露一个秘密。一名男孩的父母不相信疫苗的作用，尼尔、摩根和阿历克斯在治疗这名男孩时遇到了困难。

一位病人因为想要防止他恋童癖的冲动行为而要求做手术，而尼尔、摩根和克莱尔探讨该怎样应对他的这一请求。

两名患者的症状表明其感染可能会通过空气传播。肖恩和奥德瑞为他们治疗，医务人员则紧急确保急诊室其他人员的安全。

医院被隔离，处于混乱和噪声中的肖恩仍然感到不堪重负。与此同时，摩根为了让她的病人活下来而做出艰难的努力。

医护工作者们试图在隔离结束后恢复正常状态。与此同时，努力从病毒感染中康复的奥德瑞应对新的感情关系。

肖恩和摩根对一名患者产生了兴趣。与此同时，尼尔、克莱尔和阿历克斯努力救治一名有机械心脏的女子。

马库斯试图说服一个悲痛的家庭把他们十几岁女儿的脸捐给一个在事故中受重伤的年轻女孩。

肖恩对一个危重新生儿心急如焚的母亲直言不讳，这让新外科主任质疑是否继续留他做住院医生。

新外科主任认为肖恩是个惹麻烦的住院医生，于是设法不再让他进手术室。

由于无法加入团队进行切除患者肿瘤的危险手术，肖恩转而调查婴儿受伤的原因。

一场酒吧打斗让肖恩进了医院。摩根和奥德瑞对一位女患者的术后症状意见不一。尼尔和奥德瑞公开恋情。

为了挽救一名女子的生命，肖恩提出进行一项复杂的手术。摩根和阿历克斯竞相为一位被诊断患有癌症的老年患者做手术。

肖恩进行实验性的下巴手术。黛比鼓励亚伦更多地参与肖恩的约会生活。

克莱尔一面准备她的第一次主刀手术，一面应对复杂情况。医护人员需要在保护垂钓者战利品的前提下治疗他的伤势。

一个阴谋论者坚称他需要进行肝脏手术是因为中毒。克莱尔、摩根和尼尔治疗一名阑尾破裂的女子。

肖恩被分配进行他的第一次主刀手术。亚伦发现了一些关于黛比的事情，这让他怀疑他们的关系还能否维持下去。

在阑尾切除手术之前，肖恩应对分心的问题。阿历克斯和尼尔准备进行一项复杂的手术。亚伦需要做出一个艰难的用人决定。

尼尔和克莱尔的新病人迫使他们面对自己的伤痛。黛比的工作风格考验着亚伦。

卡丽对肖恩的浪漫攻势让彼此感到沮丧。与此同时，奥德瑞和尼尔难以将工作和个人生活分开。

肖恩准备进一步发展他与卡丽的关系。一名年轻患者必须决定是否接受一项可能改变他人生的治疗。

肖恩看望病重的父亲。与此同时，尼尔、阿历克斯、摩根和克莱尔治疗一名脊椎受伤的橄榄球运动员。

肖恩纠结于他对卡丽和丽的感情。克莱尔回忆起自己的过去。马库斯需要给一名拒绝麻醉的女子做手术。

卡丽和肖恩治疗一名有着神秘病情的超级马拉松运动员。克莱尔努力帮助一名脑瘤复发的青少年。

摩根的母亲来到圣博纳旺蒂尔医院，引发家庭紧张关系。肖恩意识到他还需要对卡丽做更多事情。

肖恩努力应对自己一夜成名的可能性。克莱尔、阿历克斯和尼尔以一个意想不到的联系来诊治一对母女。

尼尔的团队因受到偏袒而引发不满，而肖恩提出一项创新手术，将让一个小男孩第一次开口说话。

肖恩重新投入工作，克莱尔和摩根需要联手治疗一名大学生的神经系统症状。

肖恩追求丽。阿历克斯试图与儿子重建父子亲情。团队为一名有着神秘症状的年轻女子做检查。

肖恩难以应对失恋带来的痛苦，而摩根面临艰难的职业决定。一名患者的愿望影响了马库斯和奥德瑞之间的关系。

当地啤酒厂遭遇地震，圣博纳旺蒂尔医院的全体医务人员全力以赴地救治他们的病人以及同事。

在本季结局的第二部分，医生团队争分夺秒，不顾个人安危，全力挽救病患的生命。

新冠肺炎期间，圣博纳旺蒂尔的医生团队竭尽所能控制疫情和损失。

在新冠肺炎疫情发生 8 周后，圣博纳旺蒂尔团队虽取得了一些小成绩，但也遭受了又一次惨重的损失。

奥德瑞让肖恩、克莱尔和阿历克斯指导几名新手住院医生候选人。肖恩无意中侮辱了丽。

一名身怀双胞胎的患者疼痛难忍，肖恩和摩根不得不做出痛苦的决定。肖恩请丽搬回去。

因为误诊了自己的第一个患者，亚瑟内疚不已。朴医生和摩根意外建立起情谊。

奥德瑞努力克服新冠肺炎带来的情感创伤。克莱尔建议对患有创伤后应激障碍的老兵进行彻底治疗。肖恩宣布他不想再继续教学。

肖恩得知关于丽的惊人真相，与此同时，圣博纳旺蒂尔团队治疗两名个人生活复杂的患者。

肖恩准备见丽的父母，团队治疗一名精英体操运动员和她兼任教练的父亲。克莱尔和奥德瑞尝试解决问题。

团队治疗两名病史复杂的患者，而克莱尔和奥德瑞需要解决各自的问题。肖恩发现自己对一位新同事产生好感。

摩根为一名患者寻找肝脏捐献者时，一名截肢的铁人三项运动员要进行一项危险手术，以继续为癌症研究筹集资金。

亚伦为治疗一名年轻男子的脊椎而制定手术计划。一名昏迷的病人出现生命迹象，而肖恩和摩根在应对方法上发生冲突。

一位急躁外科医生的症状可能会结束他的职业生涯，于是他寻求帮助。阿历克斯和摩根在患者慢性疼痛的原因上存在分歧。

一位不速之客迫使克莱尔重新审视自己的过去。两名社交舞者面临艰难的选择。阿历克斯和摩根试图表现得像往常一样。

肖恩和丽得知他们孩子的性别。与此同时，团队治疗一名神秘的综合格斗拳手和一名先前被误诊的海军飞行员。

一场政治抗议活动发生暴力事件，团队尽一切可能挽救两名年轻枪击受害者的生命。

丽在孕期出现并发症，肖恩感到异常紧张。亚瑟因一名患者的治疗方案而与阿历克斯和马库斯发生冲突。

肖恩在经历损失后重新投入工作。克莱尔的一位政治英雄成了她的病人。马库斯与前导师相遇。

肖恩和丽去露营，希望旅行能帮他们忘记悲伤。阿历克斯和摩根因一名患者的治疗方案而争论不休。

团队前往危地马拉，在一家乡村医院治疗病人，在那里他们需要弄清能为哪些患者提供最好的帮助。

危地马拉的医院停电后，团队面临完成三台手术的艰巨任务。

Shaun and Lea's upcoming engagement party has everyone in a festive mood; a young single mother learns her son may have contracted his cancer from a surprising source; Mateo finds out if his previous issues in America will be resolved.

Dr. Shaun Murphy and the team race to save a pregnant woman's baby and find her current situation as a convicted felon complicates it even more than they realize. Meanwhile, the hospital takes on some unexpected changes that the staff are not prepared for.

Shaun confronts Salen about the many changes she has implemented since coming on at St. Bonaventure. Glassman is forced to accept his new role at the hospital.

Dr. Shaun Murphy and the team treat a young girl whose father’s personal research complicates their treatment plans. Meanwhile, Dr. Park, Dr. Reznick and Dr. Lim’s patient refuses a life-saving lung transplant despite having a family donor.

Dr. Park and Dr. Murphy treat an elderly Asian man brought to St. Bonaventure by his daughter after being the victim of a hate crime. In addition, Lea goes behind Shaun’s back to help raise his negative patient satisfaction scores.

Dr. Shaun Murphy and Dr. Alex Park must grapple with a life-and-death decision and decide between saving one patient over another. Meanwhile, Dr. Morgan Reznick goes a little too far in her attempt to win Salen’s favor.

Shaun and Lea happen upon a terrible car accident and discover a young pregnant mother who has been badly injured and needs immediate medical attention. Dr. Glassman is apprehensive when a figure from his past reaches out for help.

Now that Shaun has called off the wedding, he is forced to confront Lea about their relationship and determine what he really means to her. Meanwhile, the team debate their opinions on plastic surgery and Dr. Audrey Lim hopes to expose Salen’s cover-up over an infant’s death to take her down before it is too late.

In an effort to please Salen, Andrews takes on a high-profile case and assigns Shaun and Allen to help perform a risky surgery to restore the voice of a famous pop star.

Salen takes extreme measures when she learns that the surgical staff have joined Lim's efforts against her. The team treats a liver transplant patient whose organ donor unwittingly gave him cancer.

Dr. Shaun Murphy makes a personal connection with a precoious young patient which threatens his objectivity. Meanwhile, while volunteering at a long-term care facility, Dr. Morgan Reznick realizes she could help Dr. Aaron Glassman’s clinic by offering telemedicine services for nursing homes and care facilities.

Drs. Lim, Park and Wolke treat a woman with Valley fever and discover a secret she has been hiding from her fiancé. Meanwhile, Drs. Murphy, Allen and Andrews treat a 45-year-old virgin and help her make a big decision about her life.

While Drs. Lim, Murphy and Wolke help a teenage “biohacker” whose self- experiments begin to compromise his health, Drs. Morgan, Park, Jordan and Glassman treat a young woman who wants a controversial surgery to treat her depression and chronic pain. Additionally, Dr. Reznick looks to take the next step in her relationship with Dr. Park.

When someone mistakenly brings a hallucinogen-laced dish to the hospital's company potluck, much of the hospital staff and doctors are incapacitated -- leaving doctors Murphy, Glassman and Allen forced to take on all the hospital's cases, further exacerbating Dr. Murphy and Dr. Glassman's conflicting work styles.

While Doctor Andrews treats a foster kid for injuries sustained at his group home, Shaun and team look to Lea's expertise with cars and auto repair to help a patient whose iron lung has broken. Meanwhile, the patient's niece, a documentarian, takes an interest in Shaun.

As Shaun and Lea head toward their wedding day, a documentary film maker has chosen to follow their lives to showcase relationships and weddings of atypical couples.

Sophie takes Lea out for a day full of luxurious wedding planning. And after a near fatal oversight, Dr. Lim senses an underlying issue is behind nurse Villanueva's unprofessional behavior.

Shaun and Lea make a big life decision and are pleasantly surprised by the support they receive from their friends at the hospital. Meanwhile, when Dr. Wolke's parents show up with a revelation, Asher struggles to accept that he and his father may never truly understand one another.

Shaun and Lea’s long-awaited wedding reception is interrupted by a violent attack at the hospital and the entire team must mobilize to save the victims. Meanwhile, the trauma of seeing people he cares for in life-threatening situations is affecting Shaun in more ways than one.

On their first day as surgical attendings, Dr. Shaun Murphy and Dr. Alex Park are introduced to the first year residents they will be overseeing, Dr. Danica Powell and Dr. Daniel Perez,who make quite the first impression. Meanwhile, Lim returns to work while facing her new reality and the emotions surrounding the changes.

The team treats a famous marriage counselor after she injures her ankle from falling, but when she offers relationship advice to them, Dr. Morgan Reznick quickly spots that their patient might be experiencing something far more serious. Meanwhile, Dr. Audrey Lim is determined to get to the bottom of what really happened in the OR during her surgery and sets off on her own internal investigation.

The team operates on a military reenactor whose attempt at authenticity has created an explosive predicament that even Dr. Shaun Murphy couldn’t predict. Meanwhile, Dr. Jordan Allen and Dr. Daniel Perez are on a race against time as they search for a severed foot.

Shaun, Asher and Powell treat a young patient on Halloween with a rare hereditary disease, sending them down an uncharted path. Meanwhile, Glassman and Shaun must overcome their differences to work together to try and find a solution for Lim’s paralysis.

In the midst of a heatwave, Dr. Shaun Murphy and Dr. Danica Powell are at odds when it comes to their patient’s surgery. Their heated stalemate tests Shaun’s patience and his willingness to compromise. Meanwhile, when the hospital loses power, Lea and Dr. Aaron Glassman are forced to come up with a quick solution or risk a total shutdown that could risk patients’ lives on the 100th episode.

When a woman pregnant with sextuplets arrives at the hospital, Dr. Marcus Andrews must split the doctors into teams to ensure their health and safety following their high-risk delivery. Meanwhile, Shaun and Lea must face their own hurdles as they discuss starting a family.

Drs. Shaun Murphy, Asher Wolke and Aaron Glassman meet a patient with an infected surgical sponge that was left in their abdomen. Meanwhile, Dr. Morgan Park must face her own past when she treats the victim of a sexual assault.

Dr. Shaun Murphy unknowingly creates a competition between Drs. Danica Powell and Daniel Perez when he introduces a new performance rating system; Dr. Morgan Reznick may have crossed a line with Dr. Alex Park.

Shaun and Lea soon learn that their surprise pregnancy may also come with additional complications. Meanwhile, Doctors Park, Reznick and Allen treat a teen with Gardner’s syndrome whose past surgical history jeopardizes the outcome of his current one.

On the way to their babymoon, Lea and Shaun get a quick lesson in parenting when they rush to aid an injured dog. Meanwhile, Dr. Danica Powell secretly performs an operation on a friend that could jeopardize her career.

Shaun invites Aaron to stay with him while he has exterminators at his house and Lea realizes both men have a lot more in common than she realized. Meanwhile, Dr. Morgan Reznick wrestles with a big decision about her career and her personal life.

Shaun and Lea clash over their parenting styles and worry about what will happen to their relationship when their child is born. Meanwhile, Dr. Lim must find a way to save the damaged lungs that one of her long-time patients has been waiting for.

When a 3-year-old arrives at the ER, the team immediately recognizes he is having a stroke. However, Dr. Shaun Murphy’s diagnosis of the underlying cause doesn’t solve the problem which has Dr. Park search deeper.

Dr. Jared Kalu makes a surprise return to San Jose’s St. Bonaventure Hospital with his billionaire patient. Meanwhile, Park must treat the man his wife had an affair with and try to find a way to forgive him.

Dr. Shaun Murphy seeks legal representation to help him win a case and puts his faith in a promising, young lawyer who has obsessive compulsive disorder.

Dr. Shaun Murphy must learn how to work with Dr. Jared Kalu again and remind him that he must start all over at St. Bonaventure. Meanwhile, Dr. Murphy treats a teenager suffering from neurological problems with a very high-risk procedure.

When a patient comes in with persistent and lingering COVID symptoms, the team discovers she may be dealing with something harder to treat. Andrews and Villanueva must contend with their hierarchy at the hospital and its effect on their relationship.

Drs. Andrews and Lim clash over a patient split nearly in half, which also reveals her issues with Dr. Kalu’s return. Meanwhile, Dr. Glassman gives Dr. Murphy some fatherly advice as they await news about Glassman’s recent tests.

Dr. Marcus Andrews introduces some of the team to a patient whose optimism and faith seems to cause Dr. Asher Wolke the most skepticism in light of his own relationship with religion.

Dr. Glassman and Dr. Murphy's relationship may be irreparably damaged following a tense moment during surgery. While Dr. Reznick struggles during her parental leave, Dr. Park may just be the one she needs the most.

Shaun and Lea are heading to the delivery room and everyone from the hospital is also there, except for one very important person. Meanwhile, a tragic accident involving Drs. Perez and Kalu pulls everyone away, including Dr. Murphy.

Shaun and Lea adjust to parenthood as they debate the importance of schedule and routine for Steve. Meanwhile, Shaun takes on his first case back at the hospital with two baby patients in need of the same heart.

Shaun struggles to accommodate the newest member of his surgical team, Charlie, who interferes in a patient’s relationship with his daughter. Elsewhere, Park tackles a tricky brain tumor, and Lea and Morgan adjust to motherhood.

Shaun continues to be tested by Charlie when their newest case prompts her incessant stream of questions – all in pursuit of an answer. Meanwhile, Morgan struggles on who to name as guardian for Baby Eden should anything happen to her.

Shaun and Lea struggle to balance their parental duties with their personal lives. Meanwhile, Park and Morgan try to find the time and space to reignite their romance amidst the demands of parenthood and work, and Lim's mother makes a surprise visit.

Asher's views on the construct of marriage complicate his future with Jerome. Meanwhile, Asher also briefly revisits his religious past to aid a patient's conversion to Judaism for his fiancée.

The team must deal with a mass casualty event that forces them to put aside their emotions following a recent tragedy.

Shaun and Jordan's patient is in dire need of a kidney transplant. When they find the perfect donor, they also discover that he believes he is Jesus which could compromise his ability to give consent to the surgery.

Shaun, Jared and Charlie's young patient need his parents to agree on an important medical decision that could greatly improve his health; however, his parents are unable to agree on the correct path which spurs the team to try and intervene on behalf of their patient.

Dr. Claire Browne returns from her work in Guatemala for a personal medical examination. Elsewhere, Dr. Glassman struggles to manage Hannah, who remains unresponsive to his attempts to help. Park seeks out the perfect last-minute wedding location.

As the doctors consider their futures, they work together to solve one of the most important cases of their careers.