Pathologist Virchow tries to uphold his liberal values in a time of upcoming nationalism. Doctor Koch continues his work on battling the rampant tuberculosis. Von Behring tries, in vain at first, to join his lab while Jewish Doctor Ehrlich is welcomed for his work on colorizing cells. Ms. Lenze recovers after an appendicitis but has to work off the fees for her treatment by working as a nurse.

Spinola repays Behring for saving a life. Ida is urged to pursue an ambitious dream. Koch receives two visitors: a Tokyo doctor and the new emperor.

Koch reveals big news at the congress while Ehrlich struggles to find a doctor to deliver his wife's breech baby. Tischendorf and Ida's romance blooms.

Nurse Therese falls ill. Koch tests tuberculin on humans, starting with himself. Behring reaches a breakthrough in his work on a diphtheria cure.

Despite worrying results, demand for tuberculin overwhelms the Charité. Behring's diphtheria cure is put to the test. Ida meets Tischendorf's father.

Koch fails in one aspect of his life, but succeeds in another. Ehrlich faces a betrayal and increasing anti-Semitism. Ida rethinks her future plans.

En 1943, una estudiante de Medicina intenta usar el caso de un soldado en su tesis, mientras su hermano abogado trata de evitarle un juicio militar.

Anni conoce a su singular compañera de cuarto en el hospital. El Dr. Sauerbruch recibe al reticente Dr. Jung, que trae noticias difundidas por la prohibida BBC.

Anni y Artur tratan a Karin en secreto. Un colega le ruega a Sauerbruch que saque de la cárcel a su yerno enfermo. Martin le cuenta a Otto por qué va a la policía.

Margot y Jung atrapan a Fritsch y a Kolbe con las manos en la masa. Anni y Artur tienen un contratiempo. Sauerbruch viaja a Suiza y Dohnanyi se queda sin protección.

La enfermera Christel presiona a Otto para casarse. Artur decide sobre la vida de Karin sin consultar con Anni. Un intento de golpe de estado afecta a Sauerbruch.

A la espera de la inminente derrota de Alemania, el personal del Charité intenta atender pacientes sin recursos y descifrar lo que les deparará la llegada de los rusos.