George stalks Bree, despite her efforts to break up with him. Lynette takes charge of office politics. Carlos is paroled from prison and returns a new man, and Gabrielle is jealous of his new 'holier-than-thou' confidante. Susan meets her birth father and tries to begin a relationship with him.

Lynette tries to put a daycare center in Parcher & Murphy by recruiting employees' children to get the program started. Gabrielle and Sister Mary Bernard face off over Carlos' mission of mercy to Africa. Bree brings Andrew home and tells him about the revelation of George poisoning his father Rex and killing him. Lastly, Susan confronts her biological father's wife after she thinks they are having an affair.

Dr. Ron informs Susan that she needs a splenectomy. Gabrielle and her arch-enemy Sister Mary Bernard finally face off in church.

Also, Tom decides to apply for an empty position at Lynette's job, which leads to the arousal of past issues in their marriage. Lastly, Matthew and Danielle's relationship is found out by both their mothers, which leads to big repercussions later on for Bree and her past secret with Andrew last year.

Tom tries hard to bond with his new boss and tries to get Lynette to help him out. Meanwhile, Susan gets some help from Edie and Karl on her situation of getting health insurance before her upcoming surgery. Gabrielle becomes very attached to a temporary Chinese immigrant housekeeper who is staying with Solis' after being rescued by another slave owner employer. Lastly, Bree tries to uncover more about the Applewhites by sneaking into their house to meet Caleb.