Producer Na Young Seok goes to Phuket where the cast of “Reply 1988” is having a celebratory vacation. And he makes a prank on Jun Yeol, Jae Hong and Kyung Pyo and takes them to Africa to shoot “Youth Over Flowers in Africa”. Bo Gum who had to return from the vacation to Korea for a music show filming also joins the trip. The young actors manage to arrive in Namibia with few clothes, and they need to deal with many things from booking hotels, hiring a car, exchanging money to planning their journey.

Although Bo Gum misses his flight, he manages to arrive safely in Namibia and joins the others. Their first destination is Sossusvlei. On their way to Sossusvlei, they get to see beautiful sceneries of Africa and take many photos. They are excited about having a camping in the middle of African desert for the first time in their lives. Jae Hong cooks for the others who are tired from a long drive.

The young actors now head to a resort city, Swakopmund, where golden desert and the Atlantic Ocean meet. Bo Gum tries driving but he can’t help but give up just in three minutes for a reason. In Swakopmund, they find a fancy restaurant that serves delicious but rather expensive dishes. After enjoying the luxury, they begin to worry about their budget. Will they be able to make it to their final destination without a problem?

After having relaxing days in Swakopmund, they hit the road again to see wild animals this time. They head to Etosha National Park which is known as home to numerous kinds of wild animals. They are surprised by an appearance of a wild animal at the entrance of the park. For the second camping in Africa, Jae Hong cooks again. While having dinner, they bring back their old memories and talk about their career and friendship.

In Etosha National Park, they enjoy a variety of activities such as Game Driving. They are impressed to see the Etosha pan, a large endorheic salt pan. To celebrate the last night in Namibia, Jae Hong makes Tomato Pasta and Bo Bum brings an exotic African alcoholic drink. On the next day, they finally get to the final destination, Zimbabwe, but it is already in the afternoon when Victoria Falls is closed before sunset. Will they be able to tour Victoria Falls before it is closed?

Seeing the great view of Victoria Falls, the four young actors recall their memories for the last 11 days in Africa and they become emotional. They go rafting on the Zambezi River and enjoy one of the most thrilling experiences in their lives. Jun Yeol and Bo Gum move to do a bungee jump while the others give up.

A tent and camping equipment are set up on a rooftop of a building in Seoul. About a month after the trip in Africa, the members of Youth Over Flowers in Africa are gathered again. The camping equipment reminds them of their memories in Africa. They talk about everything they experienced in Africa from people and animals they met and the food they had. Plus, behind the scene stories are revealed.