Andrea Wyatt insists that mandatory minimums be added to a new drug policy the staff is developing; C.J. makes a mistake and sets them back.

During an online chat, the Surgeon General comments favorably on the legalization of marijuana. The controversy heightens when Ellie Bartlet tells a reporter that her father would never fire the Surgeon General. Toby asks his ex-wife, a Congresswoman, for her help in strongly persuading Seth Gillette to participate in the Social Security panel.

Stanley Keyworth revisits the White House to uncover the reason Bartlet hasn't been able to sleep since the night of the Iowa caucus; C.J. enlists Leo's help in freeing a White House reporter kidnapped while on assignment in the Congo; Toby and Andy joust over an upcoming presidential speech condemning Islamic fanaticism by name; Donna is offered a lucrative dot.com job by an old friend; Sam sparks an exchange on radical versus lipstick feminism when he comments on Ainsley's evening attire immediately after asking her to review language in Bartlet's U.N. address.

Bartlet, Leo, Josh, Sam and C.J. pull a practical joke on Toby; Sam's mission to end the Wilde campaign leads him to make a career-altering decision; Jordan backs up Leo as he deals with the Qumari; Toby continues to press his case with a resistant Andrea; and Bartlet cleans Ritchie's clock in their debate.

Election day finally arrives with the staff eagerly anticipating the outcome; Sam is increasingly concerned about the Wilde campaign in Orange County; Toby worries about the effect of Andy's pregnancy on the voters; Donna accidentally votes for Richie and tries to rectify the situation by trying to find someone who will vote-swap; Josh resists Deborah's new office rules until she reveals their basis; Bartlet has some new health issues to worry about.

The staff celebrates election night and encourages Sam to run for the seat in Orange County; Toby continues to worry about how Andrea's pregnancy will play politically for both of them; a coup develops in Venezuela; Jed and Abbey endure some interruptions at their private celebration.

Bartlet plays hardball to end the genocide in Kundu; after the entire speechwriting staff quits, Will is forced to rely on Elsie and some inexperienced interns to write tax policy remarks; the trip to California to help Sam's campaign gets off to a rocky start; Sam refuses to let Bartlet hold off the Democratic response to the Republican tax plan because it might hurt the campaign; Toby and Charlie get arrested coming to Andy's defense after a drunk accosts her; Bartlet fires Sam's campaign manager and replaces him with Toby.

Bartlet finally tells the staff the truth about the death of Shareef; Danny agrees to hold off on the story after five alleged terrorists go missing; Andy goes into labor after once again refusing Toby's marriage proposal; Zoey is kidnapped from a nightclub on the night of her college graduation.

Jed and the staff vet potential Supreme Court appointees; Toby and Andy don't see eye-to-eye on her fact-finding trip to the Middle East; Donna's parents are the unlikely inspiration for the resolution to the problems arising from the judicial confirmation process.

Donna Moss, Percy Fitzwallace, Andrea Wyatt and a couple of congressmen are in the Middle East on a fact finding mission when their cars are blown up. President Bartlet considers possible military targets to bomb in retaliation. In flashbacks, we see Donna becoming attracted to British photojournalist Colin Ayres.

The Santos campaign meets up with Rock the Vote and lots of musicians are around for a star-studded episode. Helen gives a lecture to MANA (a National Latina Organization, formerly Mexican American National Association) but her heritage doesn't help her when trying to deliver part of the Santos campaign message. Toby is being pressured by the Attorney General, Blake, to reveal his source and it's affecting his relationship with his kids. He tries a little psychological warfare of his own to get Blake to back down. Toby is also giving Josh campaign advice which includes plans to increase courtship of the Latino vote. Elsewhere on the campaign trail, it's Halloween and Toby's kids and Santos' kids are dressing up for the occasion.

Former series regulars, including Marlee Matlin, Mary-Louise Parker, Tim Matheson, Anna Deavere Smith and Gary Cole, make guest appearances as Bartlet, Santos and their staff members attend a funeral for one of their own. Also, Josh cautions Santos about getting involved in the vote for Speaker of the House.

C.J. and Will both face uncertain futures as Bartlet and his staffers prepare to leave the White House to make way for the Santos administration.