Un restaurante sirve de laboratorio para fabricar drogas. Catalina, directora de la DEA en Colombia no puede creer que su hija sea miembro del cartel de las Babys, que produce la peligrosa XY4.

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El Titi disfruta su supuesta muerte. Dayana se hace pasar por la gran amiga de Mariana, le aconseja no ir al funeral del Titi, pero la hija de Catalina enfurece y la enfrenta a muerte.

Catalina quiere ver con sus propios ojos el cadáver del Titi. Con dolor, se acerca al féretro y queda impactada. Allí descubre que alguien muy cercano al narco está presente en el entierro.

Leticia llega al evento de Berrío, asegura que la pareja del candidato es Carla, su hija desaparecida. Desde el automóvil, Lucrecia ve el show de Leticia y la sigue para hablar con ella.

Dayana mueve sus piezas, le da un ultimátum a Moncho. Si él no saca a Mariana del camino, ella hablará con Mano Negra para que lo haga a su manera muy elegante.

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Valeria gana más popularidad en el país y Albeiro no quiere creer lo que dicen de ella, solo recuerda los bellos momentos que pasaron juntos en cautiverio y la busca desesperadamente.

Albeiro sorprende a Valeria. La primera dama no tiene más opción que llevarlo a un lugar seguro para decirle la verdad y hacerle una propuesta que él no puede rechazar.

Catalina llega a la casa de retiro de ancianos donde Valeria y Alfonso participan en un evento. Al mismo tiempo, el grupo de Mano Negra deja un mensaje explosivo, mientras la primera dama ofrece unas palabras.

El artefacto explosivo está a punto de estallar en la casa de retiro de ancianos. Catalina neutraliza a los guardaespaldas de la primera dama y se bate a duelo con Yésica; ambas están claras que este puede ser el día final de sus vidas respectivamente.

Berrío confronta a la Diabla y ella al verse descubierta, le pide que guarde su secreto porque también sabe que él es un informante del FBI. Minutos más tarde, la cruda verdad sale a la luz.

Alexander descubre las andanzas de Mariana y la obliga a cumplir con una orden. El heredero de Mano Negra tendrá en su poder una carnada que obligará a Catalina la grande a verlo cara a cara

Valeria pide la cabeza de los responsables del atentado en la casa de retiro de ancianos, aprovecha la ocasión para sumar a sus adversarios en la lista negra. Catalina queda asombrada con la actitud de Mariana.

Johana se escapa de casa y va a matar a Hilda. En el medio del forcejeo, la exempleada de Salvatore aprieta el gatillo. Ahora todos sufren al ver a un ser querido tendido en el suelo.

Valeria tiene miedo y su mirada lo dice todo, está cara a cara y a solas frente a uno de sus enemigos. La Diabla quiere demostrar que es invencible, aunque esta vez, no sabe si saldrá viva.

Albeiro y Titi descargan todo el odio y fuerza acumulada. Al mismo tiempo, el equipo de la Diabla pone en marcha el supuesto operativo para rescatar al niño en manos de la Cuina y Pilar.

Catalina sufre, no está dispuesta a entregar a su nieta porque el futuro con Mariana es oscuro. Cata, la mediana tampoco quiere regresar a casa sin Hernán Darío.

Catalina Santana entra en acción y junto a sus aliados va a secuestrar a Jessica Beltrán. La exjefe de la DEA se juega su última carta para acabar con la Diabla, su eterna pesadilla.

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