MacGyver gets a shocking surprise when he tries to tell Matty that he’s quitting the Phoenix Foundation.

Three months after quitting the Phoenix Foundation and moving to Nigeria, Mac puts aside his differences with his father and returns when he hears Jack is the target of a murderous dictator he double-crossed.

MacGyver and Riley, with the help of Vasil, a distraught father, must find a way to drive a tanker filled with liquid oxygen through a region occupied by rebels and deliver it to a children’s hospital before they run out. Also, Riley helps MacGyver decide whether or not to allow his father back into his life.

When Oversight’s attempt to capture a drug cartel’s leader goes bad, MacGyver and Jack rush to Mexico to pull their boss out while racing through the heart of the country during Dia de Muertos celebrations. Also, Bozer and Riley use Halloween as a distraction to gather intel on a man accused of treason.

MacGyver and team are asked to solve a locked-door mystery when a man working inside a remote, ultra-secure international seed vault disappears.

When Nicholas Helman resurfaces to carry out a killing spree, the Phoenix is forced to get help from the one person who knows him best… his protégé, Murdoc.

When two American tourists go missing while doing a “No-Go Scavenger Hunt” through some of the world’s most dangerous countries, the Phoenix team goes undercover as backpackers to find them and bring them home alive.

Matty’s ex-husband, Ethan, asks her for help when a criminal organization, S-Company, kidnaps his wife and daughter, forcing Matty to decide if she’s willing to commit treason in order to help him save his family. Also, Riley joins Billy Colton and Mama Colton on a mission to Paris and makes a heartbreaking discovery.

MacGyver faces off with a cunning new adversary whose carefully crafted plans put Mac at the epicenter of an impossible choice: save the life of a friend, or save the lives of hundreds of innocents. Also, Mac receives new information that will drive a wedge between him and his father.

A double date descends into chaos when Mac and Desi witness a murder in the back of the restaurant, and as they work to find the killer, Riley tries to keep the secret about her and her friends’ “day jobs” from her new boyfriend, Aubrey.

After Oversight is almost killed in a bombing, he recruits Mac to help him find the suspected bomber, Mason. However, when Mason reveals he didn’t plant the bomb, the three team up to track down Codex, the shadow organization that set them up. Also, Mac meets his aunt Gwendolyn.

While Mac’s friends surround him during his time of grief, Los Angeles’ power grid is taken hostage in a ransomware attack resulting in a citywide blackout, and the team discovers the code used was written by Riley years ago