Dr. Blue opens up the clinic after Hurricane Harvey pours 30-plus inches of rain on the city of Houston, Texas; the doctors help animals affected by the storm, while dealing with the personal issues that Hurricane Harvey has brought to the city.

The doctors are honored for their contributions to the community; a goat with a twisted leg; a Great Dane with a life-threatening condition; a bulldog is rescued from a puppy mill.

Tensions run high when Dr. Blue visits a cattle ranch to castrate five adult bulls; Dr. Ross treats a hen with an injury; a puppy needs a serious surgery after being hit by a car.

Dr. Blue wants a home aquarium; Dr. Ross attempts to diagnose a dog with bizarre test results; Dr. Lavigne performs knee surgery on a bulldog; a lamb has breathing problems.

Six sugar gliders turn Dr. Ross into their personal jungle gym; a young Chihuahua with atypical heart trouble; the doctors fish with a client.

Dr. Ross examines a barred owl that was hit by a car, but he hopes will fly again; the doctors also visit an animal rescue center and get close to Texas wildlife.

Dr. Blue surprises his wife with a romantic wedding vow renewal in Las Vegas; a Schnauzer being boarded at the clinic needs medical help from Dr. Lavigne; Dr. Ross treats a very ornery parrot; a senior dog with a recurring eye mass.