Twin brothers Vincent and Frankie Martino navigate their way through the rough-and-tumble world of 1971 Times Square. Vincent crosses paths with other midtown denizens while plotting to improve his situation. Abby gets enlisted to buy amphetamines.

Vincent moves into a seedy hotel and contemplates an offer from mob capo Rudy Pipilo. Bobby hopes to take advantage of Vincent's new connections. Filmmaking intrigues Candy. C.C. shows Lori the benefits of having a pimp. Larry feels unsettled.

The appearance of an unexpected partner surprises Vincent. Rudy buys into a rival's plan to reconfigure the Deuce. Candy considers entering the filmmaking business. Abby languishes in her new job. Darlene works overtime to compensate Larry.

Rudy dangles a lucrative offer in front of Vincent. Longo uses strong-arm tactics to restore order among Bobby's unhappy construction workers. Candy attracts unwanted attention and is intrigued by a legitimate suitor. Paul questions his place at the Hi-Hat. Frankie hits a hot streak. Darlene gets a gift from Abby. Alston sees through Sandra. Bristling after a police shakedown, Vincent adds muscle in the person of Black Frankie, a Vietnam war vet.

Looking for a way out of his construction gig, Bobby tries to change Vincent's mind about Rudy's offer. Darlene returns from a trip home with a new girl, disappointing Abby. Roughed up by a john, Candy contemplates a change of careers. After getting busted, Paul explores the underbelly, and the exhilaration, of gay life in the city. With an assist from Alston, Sandra scores a key interview with a pimp.

An end-of-the-year crackdown by police in and around The Deuce sparks Vincent and Bobby. Candy tries to persuade Harvey, her adult-film director, that she can do more than act. Rudy witnesses a pivotal lower-court ruling on obscenity, and enlists Frankie and Big Mike to protect his interests in the peeps. Alston tries to convince Sandra that he's not just a “source.”

With police pushing their business off the streets, C.C., Larry, Rodney and other pimps worry about becoming obsolete. Candy eyes a different job on Harvey's set as Lori struggles with the demands of porn acting. At her wit's end, Ashley hangs out with Frankie and, later, washes up on Abby's door. Bobby is smitten with an employee.

In the Season 1 finale, Vincent balks at getting in deeper with Rudy, as expansion fever hits Frankie and Bobby. Candy gets a taste of directing, and enjoys the red-carpet perks of a major premiere. Alston finds himself in limbo at his precinct. Abby changes up the Hi-Hat's clientele; Sandra faces editorial and legal hurdles; Vincent settles a score.

On the eve of 1985, a worn-out Vincent reconnects with his ex-wife, Andrea, as his open relationship with Abby grows more distant. Despite becoming a family man, Frankie continues his risky side hustles. With the newly dominant VHS format shaking up their industry, Candy and Harvey travel to Las Vegas for an adult film convention. Now a bartender at the Hi-Hat, Loretta becomes an active member of Women Against Pornography.

Frankie takes his amateur porn business to the next level and ends up in a confrontation with Rudy, who pushes Vincent to up his profits. Candy brainstorms a new film based on the experiences of her fellow sex workers and finds that her new beau Hank is not shaken by her past. Abby and Loretta take care of Shay when she shows up to the Hi-Hat in bad shape.

Abby befriends a graffiti artist named Pilar and takes a surprising trip downtown. Candy sets a firm line with Hank when it comes to money. Todd re-examines his priorities and asks for Paul's support. Melissa is forced to face her past.

Lori returns to New York for an audition and runs into some familiar faces. Candy speaks to her critics at a Women Against Pornography meeting. Alston takes a drastic step to deliver for Goldman. Vincent and Frankie celebrate an eventful birthday.

A distraught Vincent follows a lead down a dangerous path. Paul reaches out to Tod's parents. Candy battles Harvey over her latest script. Lori hits the feature dancing circuit. Abby reflects on her choices. Bobby does right by Black Frankie. Alston defends the plan to clean up Midtown. Gene reckons with his conflicted personal life.

In the wake of a personal loss, Candy finds the emotional core of her latest movie. Abby confronts Vincent after she makes an alarming discovery. Paul turns to activism as the AIDS epidemic continues to ravage New York's gay community.

A struggling Lori turns to Candy for help before revisiting The Deuce. Candy makes a surprising deal to secure funding for her film. Abby takes a stand against the latest phase of Midtown redevelopment. Tommy explains the new world order to Vincent.

Big changes come to The Deuce as Gene sees opportunity in the city's public health crisis. Vincent looks to get out from under the mob's thumb and makes peace with Abby. Candy makes a critical choice in her relationship with Hank. Series finale.