Professor Wiseman is too busy to keep an exercise routine. So when she signs up to run in a fund-raising footrace, she enlists George as her personal trainer to help whip her into shape. George quickly learns there is more to exercising than meets the eye, and teaches Professor Wiseman that the keys to running are stretching, keeping hydrated, staying motivated and pacing yourself.

George has just been made an Honorary Junior Sprout of Country County and is thrilled to be on his first trip with the troop. But when the troop gets lost in the woods, George not only finds himself separated from the group but he also discovers a man sawing branches off a tree — a clear violation of Sprout rules! Can George prevent the man from harming more trees and earn his Sprout stripes along the way?

After days of Gnocchi choosing to eat cat food over Chef Pisghetti's famous creations, the Chef decides to stop cooking and close the restaurant! Not wanting to lose his favorite ravioli, George follows Gnocchi to find out why she stopped liking the Chef's food, but all she does is take naps, roll in the dirt and sneeze an awful lot. Her sneeze sounds an awful lot like the Man with the Yellow Hat when his flower allergy flares up. Can George diagnose Gnocchi in time to save Chef P's restaurant?

Armed with a cool new monkey-sized vacuum, George watches with amazement as his new "toy" sucks up everything in sight... including some of Mr. Stamp's rare stamps! Inspired by a TV superhero, George dons a cape and embarks on a citywide "cleaning" spree, using his little vacuum to suck up everything from bird food to dog biscuits to a winning lottery ticket. When the townspeople can't catch up to the cleaning monkey, will they view George as a Superhero Vacuum Monkey or a Super Villain?

George opens the chicken coop at the Renkins' farm and finds - wait -- a little girl?! Mrs. Renkins introduces George to Allie, her 5-year-old granddaughter who's spending her summer in the country. Allie is thrilled to meet George and practically runs out of breath asking him a million questions. She wants to know what it's like to be a monkey, and George spends an entire day showing her, which includes climbing high in a tree to see where Jumpy squirrel lives. When George climbs down the tree though, he finds that Allie is afraid to follow him. Not that Allie minds being stuck in the tree…she speaks squirrel, you know. Still, George knows girls can't live in trees. He needs to bring out Allie's inner monkey and get her down from the tree!

Hundley takes it upon himself to return the toy a baby dropped in his lobby. But when George sees Hundley racing down the street with the toy in his mouth, George thinks he wants to play, and this delays Hundley. Hundley is not happy to see the baby drive off in a bus sans toy and is even more upset when Gnocchi, who wants in on the fun, grabs the toy and disappears through Pisghetti's basement window. George and Hundley follow Gnocchi into the basement, only to have the door lock behind them. Uh-oh. George and Gnocchi can climb up and out the window, but Hundley can't. George comes to the rescue by constructing a ramp leading to the window that even the littlest Dachshund legs can climb. Now they just need to figure out where that baby went.

George has never seen a farmer's market before and finding one on his doorstep is just about the best thing ever -- until he drinks Juicy Jay's special blended juice and then that's the best thing ever! When the farmer's market leaves and there's no more juice, the Man with the Yellow Hat and George decide they need their own juicer. As they start to unpack their new purchase, the Man gets called away. A smart monkey can figure out a juicer on his own and recreate the special juice, right? It's certainly not as easy as it seems and certainly not a mess-free process! Although he has a few missteps (amazing how mushed vegetables can fly all the way to the ceiling), George masters the juicer. But will he be able to make the juice he and the Man think is the best ever?

George loves imitating the Cerulean Warbler's distinct chirp and is aghast when the Man with the Yellow Hat tells him that his favorite bird is on the endangered species list. Not to worry, the Man just wrote a book to make people aware that the bird needs assistance. But unfortunately, stores don't want to carry the book because, at 1,400 pages, it looks like a boring scientific tome. Fortunately, George runs into Steve who has lots of idea for promoting his lemonade stand. This prompts George to come up with an idea of his own -- paint an empty billboard with a razzle-dazzle picture to help promote the book. Easier said than done and even when done, will it help sell the book and spread the bird word?

George doesn't feel so well. There's a germ lingering inside his body that has him sneezing and coughing, while making very sleepy. In a cold-induced dream, George and Gnocchi travel inside George's body, chasing a blues-singing germ named Toots and his harmonizing Germettes through the monkey's nose, stomach, and lungs as George tries to rid his body of the germ.

A dry spell has lowered the water level of Lake Wanasink Lake, which leaves one of George and Allie's fish friends trapped in a small pond away from its family! George digs a canal with a lock between the lake and the little pond, but he can't get his fish friend to use it. Can a monkey and girl find another way to get the fish back to its family?

George is excited to some day go to school, so Allie decides that he should visit her kindergarten class for a day. But, as it turns out, there are lots of rules about what you can and can't do and George is a bad follower. But things change when George and Allie decide to build a castle in the classroom based on a book they read.

Charkie is at a dog obedience class, and the next day is the final test! Since Betsy has a concert, George (and Hundley) must recreate the obstacle course and make sure Charkie can do it in under a minute to pass.

George and the Man with the Yellow Hat convince Professor Wiseman to take a well-deserved break from work. But a stuck pickle jar, a tangled hammock, and a duck floating away with the Man's beloved hat turn their relaxing picnic in the park into one stressful afternoon. Still, could a day of creative problem solving be exactly what the monkey ordered for Professor Wiseman?

Charkie will do anything to get what's inside of Aunt Margaret's parcel, but George promised he'd keep it safe! After twisting, turning, flipping, and rotating the box, George is able to get it out of sight, but Charkie's keen sense of smell makes it impossible to stay hidden for long. Can George figure out how to distract Charkie's super sense long enough to get the box back to Aunt Margaret?

It is the hottest day in the city and the city keeps suffering from blackouts. But there is one place left with electricity: the museum which just converted to being entirely powered by solar power. When George learns how the sun's light can be absorbed and turned into electricity, to do things like charge batteries, he tries to charge up several things at home such as his toy UFO or the cordless phone. But then he learns how solar power really works to make electricity. Then, when another blackout makes the Man unable to cook his lasagna for the museum's big power upgarde party, he and George learn that the sun's heat can also be used to cook things.

The Man with the Yellow Hat is showing George around his old neighborhood when they come across the abandoned and run-down Bijou that The Man used to visit all the time when he was little. Mr. Glass wants to tear the building down but George gets the idea that they should fix it up and reopen it.

Professor Wiseman wants to makes something creative for the bake sale at Betsy's school. But she believes that the key to cooking is to experiment with different amounts of different ingredients and as a result her cakes come out floppy, gross, and VERY sticky. When Professor Wiseman and George visit Chef Pisghetti he says that cooking is not about testing and experimenting like science and you need to follow a recipe exactly for the food to come out right.