Dr. Dee swaps roles as she takes her own dog to a specialist in Anchorage for eye surgery. There, she reconnects with her step-daughter to check on a barrel racing horse. Meanwhile, a remote clinic takes a turn for the worse for Dr. Terry and Nicole.

Dr. Dee and her husband Ken help the remote villages of Alaska by hosting a vet clinic in a town of just 107 residents. Back at Animal House, Dr. Dee has a life or death emergency on her hands with an Akita apparently suffering from a gunshot wound.

Dr. Dee starts fundraising for a no-kill animal shelter in Fairbanks with a pet tricks competition. A pot-bellied pig named Lilly Lou undergoes a surgery full of surprises. Dr. Dee's long-time friend has a stallion with a possibly deadly tumor.

At Animal House, Dee sees a Chihuahua with a life-threatening condition, a vocal Macaw that needs a beak trim and a dangerously ill newborn calf. At home, Dr. Dee and her husband Ken welcome seven fainting goats to the family.

Dr. Dee visits a ranch to check on a pack horse named Red, but she has to be careful. Red kicks like a mule! Dr. Terry and Nicole head to Arctic Village for a remote clinic. Dr. Dee holds down the fort treating a dog with a mass that looks cancerous.

Dr. Dee flies her mom to a remote vet clinic in Manley Hot Springs, Alaska. Back at Animal House, a Rottweiler may have bone cancer and a bunny has an abscess that just won’t quit. It’s all smiles when several St. Bernard puppies visit the clinic!

Dr. Dee flies to Healy, Alaska for a remote clinic. While performing a spay, she notices a dog has tumors. Outside Fairbanks, Dr. Dee also gets Nugget the Bull ready for breeding season, while Dr. Terry gets a big surprise giving shots to kittens.

Dr. Dee and her husband Ken respond to an emergency, flying to rescue baby owls whose parents were killed by an eagle. At Animal house, Dr. Dee's dog becomes a blood donor for a lab with an auto-immune disease, and a cat undergoes stem cell therapy.

Dr. Dee must perform a three-hour surgery to save a dog's life. Dr Dee & her husband Ken head to Yakutat, Alaska, a village that hasn’t seen a veterinarian in two years! Dr Dee also visits a giant Tegu lizard and several snakes for a wellness check.

Dr. Dee returns to Ruby for a remote clinic. At Animal House, Dr. Dee treats a malnourished bunny and tackles a border collie puppy with a congenital issue and a rescued cat who may have an incurable disease called feline immunodeficiency virus.