The Saint corners the trio. Jesse makes a deal with the killer Cowboy. Jesse races to save Tulip and Cassidy.

Jesse connects with an unlikely source and learns more about God's whereabouts. Tulip can't forgive Jesse when she finds out he's been lying to her.

As Cassidy falls in with a group of mysterious strangers in New Orleans, Tulip and Jesse deal with the fallout of a failed escape from Angelville.

Annville, Angelville and the Grail team up to steal souls in New Orleans and Osaka in a last-ditch effort to satisfy Gran'ma and save the world.