It is the fiftieth anniversary of the disappearance of Sussex student Maggie Hancock and Maestro Vespemi, the school's music teacher. Every year on the anniversary the Maestro's ghost comes looking for Maggie.
The students at Sussex Academy cannot figure out what is wrong with the usually stern and strict Ms. Stratmann--she is smiling and laughing all the time and she is even complimenting Stink on his practical jokes.
Ancient native ceremonies and a mysterious tribal trickster follow Shirley Holmes as she tries to find out what happened to a box of two-hundred-year-old bones that has gone missing from a reservation.
At the observatory, Bart hears signals from outerspace and runs into Shirley on the case. When two officials show up, it becomes clear that the man in charge of the observatory is not who he says he is.
Mr. Howie stays at the Howie Farm, but when he stays their longer than he had expected, Shirley has questions. Not only do the animals on the farm act nuts, but there is a ghost legend, and a feud between the Howies and the Wilkinsons.
Math classes at school are suspended due to budget cuts. Instead, the school receives new electronic equipment. Bo attends another school that has banned electronics and kept math in order to find out what's going on.
Strange incidents are keeping the Sussex Hornets from winning the basketball championships. After one of the 'accidents' causes Bo to hurt his ankle, Shirley decides to find out who is behind the sabotage.
When Shirley recieves an orchid from a secret admirer, a bee sting sends her into an anaphylactic-shock-induced dream where she tries to figure out who was the sender, with the help of clips from past shows.