Bruce Banner's latest attempt to rid himself of the Hulk is shut down by General Ross and Major Talbot. Now being held in the Gamma Base, Bruce recalls how he became the Incredible Hulk.

On the run from General Ross, Hulk encounters the Gamma Mutant Warriors. But Abomination reappears and captures Bruce. He is taken to The Leader, who wants the power of the Hulk for himself.

Bruce befriends Mitch McCougthen, a man looking for a better life for himself. Their efforts to cure Bruce of the Hulk go horribly wrong when McCoughten is suddenly turned into Zzzazk. Can the Hulk defeat a being of pure energy?

Bruce Banner and Rick Jones are in L.A., seeking the help of wealthy industrialist Tony Stark. Iron Man, War Machine and H.O.M.E.R. will have to find a way to cure Bruce of the Hulk before S.H.I.E.L.D. Agent Gabriel Jones arrives.

Bruce is in Canada looking for the help of his old friend, Dr. Walter Lankowski. When he does find him, Bruce learns his deadly secret.