A couple years out of college, Cooper Barrett still doesn't have his dream job, he's possibly fallen for his across-the-hall neighbor, Kelly Bishop, and he can’t seem to avoid major trouble, along with his roommates, Neal and Barry.

After sales for their hangover cure are slower than expected, the guys decide to take part in a drug trial for quick cash, but their plans are unexpectedly derailed by Paul Abdul.

When Kelly tells Cooper that the state of his apartment is ruining their chances at taking their relationship to the next level, he sets a meeting with their landlord, Virgil, in an attempt to fix things around the gang's place. But after their first meeting takes a turn for the worse, an epic battle between landlord and tenant ensues.

Cooper gets all the credit for Barry's grandmother's hangover cure, leaving Barry and Neil frustrated; the gang bands together to stop a rival CEO from stealing the hangover cure crown.