Patterson and her puzzle-expert boyfriend, David, decode a tattoo clue that sends the team to the Centers for Disease Control (CDC). While at the CDC, the team discovers a hidden message on Jane's body that uncovers a plot that could have catastrophic global consequences. Meanwhile, Jane and Weller grow closer.

In the thrilling mid-season finale the team goes after a group of sleeper spies that have just been activated and race to stop a slew of assassinations.

After an armored truck is robbed, the team discovers that the stolen goods are chemical weapons and they must race to thwart a terrorist plot. Meanwhile, Jane grapples with a confusing memory of Weller - while growing even closer to Oscar. Meanwhile Patterson receives a phone call from someone from her past.

When a mysterious young girl with a tattoo connection falls into Borden's care, he brings her case to the FBI team -- but her ties to a terrorist organization prove dangerous for all of them. Meanwhile, a conflicted Jane starts to grow close to Weller again, and friendship blossoms between Borden and Patterson.

After a set of tattoos produces multiple leads, the team divides into unlikely pairings to chase down a deadly underworld courier.

Zapata's transgressions catch up to her, sending her to jail alongside a potentially powerful Sandstorm asset named Devon. Weller and the team must go to exceptional lengths to help Zapata out.

While Jane and Weller hunt down a collective of dangerous computer hackers, Patterson and Rich Dot Com must work together to hide an explosive secret from their past.

While Jane and Weller partner with a mysterious man from Jane's past to find a missing person, the team races to stop an arms deal.

The FBI team and Avery attend a gala hosted by their target Hank Crawford in hopes of arresting him. Roman grows closer to the Crawfords.

The entire intelligence community is put in jeopardy when Remi co-opts an FBI case.

Jane and Weller's romantic getaway is cut short when the team must stop Madeline Burke's plans to blow up a building and crash a plane that turns out to be more than the average commercial airliner.