I 1942 kæmper superheltene for at beskytte Albert Einstein og forhindre, at nazisterne sammen med Damien Darhk udraderer New York med en atombombe.

Teamet befinder sig fortsat i 1942 og kæmper mod en vanvittig nazist for at redde Justice Society of America – og Nates bedstefar – fra at blive udraderet.

I deres jagt på kommandør Steels fragment infiltrerer teamet NASA i 1970'erne og blander sig i Apollo 13s mission til månen.

When Mallus' power over Sara resurfaces, she unwittingly becomes the bearer of one of the Totems. Rory must conquer his dark side in order to wield his own Totem power to help save the crew. Meanwhile, Agent Sharpe notices that something is wrong and recruits someone unorthodox to help.