Someone is killing off potential Librarians and it's up to Flynn Carsen and his new Guardian, Colonel Eve Baird, to save the three that are left.

The Serpent Brotherhood is trying to return magic to our world. Flynn, Colonel Baird, and the potential Librarians must stop them before it's too late.

When the dragons sleeping beneath the earth threaten to awaken and wreak havoc around the world, Flynn returns to help find their hidden treasure.

Baird begins moving through alternate timelines that reveal the destinies of the librarians.

While Jenkins discovers there's something wrong with the Library since it returned from the Void, the Librarians all find themselves drawn back together after having been off on their own for months, to solve the mystery of a massive storm that has parked itself over Manhattan. They soon discover the culprit in both cases is none other than Shakespeare's Prospero.

Prospero summons other fictionals in order to retrieve parts of his staff; the librarians find themselves pitted against Frankenstein's monster and Sherlock Holmes' nemesis Moriarty; Flynn and Baird have a disagreement.

While chasing one of the Library's missing artifacts, Flynn is kidnapped by a mysterious stranger with both amnesia and a collection of all the Library's missing artifacts. Soon all of them are in pursuit of the Staff of Zarathustra before it falls into the hands of Prospero.

The team has scattered, all living the ideal versions of their lives. Soon these “strangers” are drawn together to solve a supernatural mystery – the appearance of Ariel, the sprite bound to Prospero's service. Can the Librarians do what no other human has ever been able – turn their backs on their own ultimate happy endings?

The Librarians discover that Prospero's renewed magic is wreaking havoc with the technology of the world. He is recreating an idyllic forest utopia, whether we want one or not. In order to stop him, Flynn and Baird must travel back to 1611, while the rest of the team battles Prospero in the present. Little do they realize that they can only defeat Prospero in each time by finding a way to work together – separated by five centuries.

When the Egyptian God of Chaos inhabits a human body, he attempts to release Pure Evil into the world, thus beginning the final battle of Good vs. Evil. In order to stop him, the Librarians must decipher a series of clues within a science museum, including a mysterious warning spoken by exhibit mannequins that have come to life.

Flynn leads his fellow Librarians on a mission to rescue kidnapped Charlene, unwittingly ensnaring them in a subterranean trap filled with ancient Egyptian werewolves, led by nemesis Apep, who are determined to kill the Librarians once and for all.

In order to stop the spread of pure evil, the team must find the Eye of Ra and unravel the mystery of the Bermuda Triangle; Flynn must pass a series of tests.

The obnoxious Cindy Kroger has suddenly become super-popular thanks to a magical love potion. The Librarians must stop her before she launches a love missile that would force the whole world to become her fan base.

A rash of people spontaneously combusting leads the Librarians to a holistic spa run by vampires, who have discovered the secret to walking in the sun.

When the Monkey King's sacred homeland of Shangri-La is taken over by a ruthless collector of magical artifacts, the balance of the Universe is put in jeopardy, forcing all the Librarians to come together to help save the imperiled land at what could be a terrible cost.

The Librarians' two-front battle comes to a head when the Library is simultaneously infiltrated by DOSA and Apep. Flynn, Baird, Stone, Cassandra, Ezekiel and Jenkins must all put aside their differences in an attempt to save the Library, the world and themselves.

When a secret sect of the Vatican Church unearths an ancient map detailing the locations of the four cornerstones of the Library of Alexandria (the original Library), it’s up to Flynn and the Librarians – with the help of an unexpected ally – to stop them before the stones can be used to destroy the Library.

When people begin getting hurt in the unluckiest of ways, the Librarians are led to a casino where the owner appears to possess an artifact capable of stealing people's luck. Despite falling under the bad luck curse themselves, the Librarians must turn the tables before the plague of bad fortune spreads to the wider world.

When Santa takes Flynn, Baird and Jenkins on his first vacation in centuries, he leaves his beloved sleigh in the care of the Librarians. But when Ezekiel's career criminal mother steals the magic door, they must use the sleigh to save her, as well as Christmas itself, from Santa's Grinch of a brother, the Patron Saint of Thieves.

When Flynn and Baird are sucked into Baird's favorite classic Film Noir movie, the Librarians are drawn into the world of movie magic - literally - where they'll need to perfect their lassoing skills, sharpshooting, and snappy dialogue if they're going to make it out alive.

A Librarian from the past teams up with the Librarians of the present to take down an ancient and powerful enemy let loose in the modern day. When superfan Flynn is met with the prospect of teaming with his Librarian hero Darrington Dare, he could not be more excited, until Darrington leaves the Librarians with this dire warning: There can be only one Librarian - ignore at your own peril.

When Baird goes after Nicole Noone in an attempt to repair her rift with the Library, she ends up joining Nicole in a mission to retrieve a dangerous artifact before it falls into the hands of Russian grave robbers. But can she convince Nicole to forgive the Library and return home with her? Or, will Nicole open Baird's eyes to the dangers of a Guardian dedicating herself, heart and soul, to the Library?

After the world is morphed into a horrible and unrecognizable place – one where the Library never existed – it's up to Baird to bring the Librarians together before this bleak, knowledge-less world becomes the new reality.