The Planet Express crew take a space cruise vacation. Leela tells Captain Zapp Brannigan that Fry is his boyfriend and Amy tells the same thing to her parents. Bender falls in love with a rich female robot. Problems start when the spaceship approaches a black hole.

When Hermes takes a stress-relieving vacation, replacement bureaucrat Morgan Proctor becomes infatuated with Fry. Bender threatens to publicize their affair, but Morgan removes Bender's memory and hides it within the cavernous Central Bureaucracy.

A mission to collect honey from deadly space bees apparently leads to Fry's sting-induced death. Leela is wracked with remorse, until Fry visits her in her dreams. As Leela's hallucinations intensify, she begins to suspect that she might be going crazy.

In order to compete in the Fembot's division of the 3004 Olympics, Bender is surgically rebuilt to become a woman. Her trashy behavior catches the eye of Calculon, with whom she develops a strong and confusing celebrity relationship.

An episode describing the three winter holidays of the future: X-Mas, Robonica, and Kwanzaa.

An alien who does not understand the concept of gender conducts experiments on the crew, changing all their genders.

Leela and Amy become addicted to the performance enhancing drug known as "Nectar" to increase their chances of winning at the epic sport of the Butterfly Derby.

Hermes replaces parts of his body with robotic counterparts so as to increase his productivity.

The crew finds out Professor Farnsworth's parents are still alive on the Near Death Star.

The crew stages a casino heist to recover stolen property from the Robot Mafia.

Bender and Zoidberg travel through time to attack Robot Santa.

A pandemic ravages future Earth.