Roxie and Veronica are two gorgeous young women - who also happen to be highly trained contract killers. While on an errand for their boss, an unpleasant surprise in the trunk of their car turns this lethal pair into hunted targets.

Veronica & Roxie soon find their lives at risk. Mother deploys her two best hunters in Julian (Clifton Collins Jr.) & Kyle (Nathan Keyes) to eliminate the girls & bring the boy, Tyler (Jakob Salvati) in. Meanwhile, FBI Agent Frank Barnes (David Arquette) continues his search for Tyler.

Veronica and Roxie fight their would-be-assassins as they become the reluctant protectors of Tyler -and uncover the secret as to why the young boy is in such high demand. In the meantime, Barry is double crossed by Mother and moves up his prison escape plans to settle the score.

Barry Madden escapes from prison to help re-capture his son Tyler who is the key to accessing the embezzled funds from Barry’s lucrative and illegal ponzi scheme. As Mother’s hit squad close in on them, Veronica and Roxie have no choice but to team up with Agent Barnes to keep Tyler safe.

After Tyler is captured by crime boss Mother, Veronica, Roxie, and FBI agent Barnes fight to reunite the young boy with his mother, Eileen. In a classic bait-and-switch, they lure Barry into a trap and force him to make a deal with Mother that will hopefully ensure Tyler’s safe return.