When the assistant vice minister of Timor-Leste suddenly dies during a meeting with Elizabeth on the first day of the U.N General Assembly, she becomes suspicious after the president of Timor-Leste ships the body back without a proper investigation. Also, a “fake news” story surfaces claiming Elizabeth is responsible for the minister’s death, and Dmitri returns to work with Henry.

While Elizabeth is in Libya to help negotiate an end to their civil war, a tragic accident with her chauffeured car embroils her in an urgent situation to secure medical care for a gravely wounded local girl.

With a government shutdown looming, Elizabeth must think outside the box to help fund an electrical grid in a Syrian refugee camp, before riots break out in the country due to the lack of electricity and water. Also, Henry searches for Dmitri when he goes missing.

As the government shutdown shows no sign of progress, Secretary of State McCord must negotiate an agreement between the White House and its opposition led by Senator Morejon. Also, Elizabeth is having trouble finding a suitable replacement for the chief of staff position.

Elizabeth is determined to continue to hold a human trafficking conference in Kyrgyzstan despite the inappropriate actions by a U.S. ambassador. Also, Elizabeth and Henry worry about Alison when she keeps coming home from college.

Henry disagrees with the President and Elizabeth when they refuse to negotiate with terrorists for the release of an American CIA agent who was captured by the Taliban in Afghanistan. Also, Elizabeth tries to be supportive of Stevie who is going through a difficult time.

When a Russian dissident flees to the U.S. after contracting smallpox, Secretary of State Elizabeth McCord and retired U.N. Ambassador Kat Sandoval must work with Russian Foreign Minister Konstantin Avdonin to contain the outbreak.

Secretary of State McCord and her staff work with the Mexican government to extradite a Mexican cartel leader to a U.S. prison in an effort to diminish the opioid crisis. But after he escapes during transport and a journalist who secured a gloating interview with him while on the lam is murdered, Elizabeth’s urgency to find the leader escalates.

Secretary of State McCord reluctantly agrees to host a holiday party in the hopes of persuading senators in attendance to pass a treaty that requires countries to destroy landmines. Also, Henry tries to find evidence that the Senate Majority Leader exchanged information with the Russians.

Secretary of State McCord struggles with the realization that she may need to advise the Afghan government that a compromise with the Taliban may be better than a war with them. Also, Henry uses Dmitri as bait to convince a Russian spy to help the U.S., and Daisy returns from maternity leave and decides to finally tell Joe’s mother about the baby.

When Vice President Hurst feels threatened that Secretary of State McCord is vying to be the next president, she attempts to set Elizabeth up for failure by promising that Americans will continue to be able to adopt Russian orphans, despite the potential ban by Russia’s president. Also, Elizabeth and Henry find out Stevie is dating Dmitri after he is followed by a Russian assassin.

After President Dalton hears about a sonic attack at the U.S. Embassy in Bulgaria, he thinks Russia is to blame and uncharacteristically threatens them with military force, leaving his cabinet concerned about his mental status.

Elizabeth seeks creative solutions when the president of Sri Lanka's psychic convinces him to not move forward with a trade agreement with the U.S. Also, Alison grapples with guilt for missing the warning signs after her college roommate attempts suicide, and Henry makes an abrupt career decision.

Jay and Kat devise a way to help persecuted foreign LGBTQ citizens escape their country while their U.S. homeland security applications are processed. However, when the country closes its borders, Jay and Kat are forced to change that plan quickly, as it could now threaten their relationship with neighboring allies.

Elizabeth and the team are caught in an uncertain situation when they are about to award a foreign leader with the Medal of Freedom but learn he may have known that a minority group in his country is being persecuted. Also, President Dalton doubts his ability to return to office after being cleared by his doctor, and a past family grievance is brought to light when Henry’s sister pays a visit.

As the 20th anniversary of the American embassy bombing in Mali approaches, emotions run high among the State Department staff, who had personal connections to lives lost that day, including Elizabeth, who must decide if the U.S. should lift sanctions against the country deemed responsible. Also, Henry tries to help Jason break up with Piper.

Senator Morejon puts phase two of Elizabeth’s U.S./Iran arms deal in jeopardy when he asserts that Iran funneled money from phase one of the deal to fund a recent bombing that killed an American citizen. Also, Henry mulls over the option of becoming the chairman of the new military ethics department at the National War College.

Elizabeth’s negotiations for a security agreement combatting gang violence in South America becomes complicated when she attempts to free an American recently kidnapped there.

Elizabeth is attending a summit in Montreal to resolve territorial claims of the North Pole when an activist group detonates a bomb and she can’t locate Jason and Piper. Also, things take a turn for the worse when Elizabeth learns that Russia was involved in the bombing, and Henry helps one of his students work through a difficult decision.

Elizabeth must watch what she says and does when she deals with a refugee situation while being shadowed by Neal Shin, a newspaper reporter who may use his access to write a tell-all book.

When terrorists threaten to cause a flood in the Middle East that could kill millions of people, Elizabeth’s hopes of getting a neighboring country to close the dam fade after the government suddenly goes dark during a coup. Also, Stevie is tasked with finding Russell an activity that will help manage his stress.

Elizabeth and cabinet members brace for the fallout at home and abroad as President Dalton prepares for a retaliatory nuclear attack on a country that has reportedly just launched missiles bound for the U.S.

In the aftermath of a deadly attack on the White House, Elizabeth tries to keep a major nuclear disarmament deal from falling apart while a manhunt for the attackers brings D.C. to a halt. For advice, Elizabeth turns to former secretaries of state Madeleine Albright, Hillary Clinton and Colin Powell.

When Elizabeth discovers that the White House attackers had support from overseas, she tries to hunt down those responsible without starting a war. Also, Henry comes face to face with one of the attackers.

Elizabeth flies to Fashion Week in Milan to face off against the Chinese Foreign Minister over an anti-sweatshop treaty in the aftermath of a tragedy. Also, Daisy struggles with feelings of fear and pessimism over her baby’s future, under the threat of rising nationalism in the wake of the attack on the White House.

When the remains of U.S. soldiers who served in World War II are uncovered in Southeast Asia, Elizabeth’s hopes of bringing them home quickly fade when a stubborn leader stands in her way. Also, Henry and Stevie find themselves publicly targeted by a restaurant owner who is angry about Elizabeth’s policies, and Alison volunteers for a local congressional campaign.

Henry finds himself at the center of an international incident, when he comes to the aid of an ex-girlfriend at a religious freedom conference in Thailand, after she is imprisoned for condemning the monarchy. Also, Elizabeth helps Jason navigate the pressure of preparing for college.

When the eruption of an Icelandic volcano strands Elizabeth at an airport in Ireland with the Turkish foreign minister, she tries to broker a deal with him to save the lives of thousands of Syrian refugees. Also, Henry gives advice to Alison about an awkward topic.

Vice President Teresa Hurst asks Elizabeth for help when a surrogate carrying her future grandchild is arrested in Laos for human trafficking. Also, Henry tries to protect Stevie from danger when he suspects that she’s being followed by a Russian operative, and Blake deals with the demanding and costly instructions of a delegation of Japanese gardeners.

When Haiti’s democracy is threatened by a president who refuses to step down after losing the election, Elizabeth tries to solve the problem without resorting to military action. Also, Blake has one week to find a new job before Elizabeth fires him as her assistant.

Elizabeth and Jay work to keep an historic agreement between Serbia and Kosovo from falling apart, after a mass grave is discovered in Serbia dating back to the Kosovo war. Also, Henry deals with a bizarre encounter with Secretary of Defense Gordon Becker.

Elizabeth goes head to head with a U.S. governor over the state’s new policy of separating unauthorized immigrants from their children.

Elizabeth goes head to head with a U.S. governor over the state's new policy of separating unauthorized immigrants from their children. Also, she and Henry plan to renew their wedding vows.

Elizabeth must salvage a deal with a military contractor by supplying fighter jets to Taiwan, but she risks triggering a war with China in the process. Also, Daisy gets frustrated with Matt for failing to help take care of her dog like he promised.

When innocent Syrian children are killed by an American-made cluster bomb, Elizabeth races to figure out what went wrong before Russia can use it as an excuse to escalate its military presence in the region. Also, Russell faces a PR nightmare after he gets into a heated argument with a homeless protester.

When a group of American missionaries become hostages during a violent uprising abroad, Dalton must confront demons from his past in order to help Elizabeth secure their safe return home. Also, Stevie takes over Russell’s social media presence, and Henry helps his niece, Sarah, mentally prepare for her military deployment.

Elizabeth visits the Middle East to finalize a deal to bring U.S. troops home, but complications arise when a local woman’s life is threatened by rumors of a romance with one of Elizabeth’s staffers. Also, Henry provides relationship advice to Elizabeth’s brother, Will.

When a super typhoon threatens a small Pacific island, Elizabeth tries to relocate its population before the storm makes landfall. Also, Henry gives a speech to an evangelical group about climate change.

While Elizabeth is away on a retreat thinking about her presidential campaign, her staff tries to secure an international agreement to protect citizens who have been displaced due to global warming. Also, the staff works to contain a measles outbreak that threatens the life of Daisy’s daughter, Joanna.

A NATO ally carries out a state-sponsored assassination attempt against one of its own citizens, who is also a U.S. resident and old friend of Elizabeth’s. Also, Alison starts dating the son of one of Elizabeth’s political rivals.

As Elizabeth prepares to officially declare her candidacy for president, she must deal with fallout from a news article alleging she had an affair with President Dalton during her CIA days. Also, Mike B. and Jay adjust to the growing pains in their expanded roles as campaign staffers, and Elizabeth calls for a UN criminal tribunal against Myanmar military leaders over their treatment of the Rohingya.

As Elizabeth prepares to leave the state department and announce her run for president, terrorists attack the United Nations delegation in Geneva that is there to sign the climate migration treaty.