A ruthless defense attorney and no-nonsense law professor at a Philadelphia university selects a group of her best students to work at her firm.

It’s the day after Sam’s murder and the students are called in to help Annalise find her missing husband, but just how much does Annalise know? And when a surprise visitor shows up in town, getting away with this murder might not be as easy as the students had hoped.

With Wallace Mahoney’s murder unsolved and Frank’s whereabouts unknown, the "Keating 5" struggle to move on with their lives as they enter into their second year of law school. Meanwhile, Annalise’s reputation at Middleton University is on the line, so she creates a criminal law clinic where the students will compete to try their own pro bono cases. Annalise also wrestles with a decision involving Frank that could change everything.