Liv and Clive investigate the murder of a journalist working on a story linking psychotic episodes in a small number of consumers to the energy drink Max Rager. Liv goes straight to the top at Max Rager HQ and questions the man in charge, Vaughn Du Clark. Meanwhile, Ravi tries to help Major who continues to believe he's going crazy.

Liv eats the brains of a recently murdered trophy wife who was pushed to her death from the balcony of her stunning architectural home in the hills by a hired hit man. A Pinot Grigio-sipping, suddenly fashion obsessed Liv and Detective Babineaux begin questioning suspects in their search for the original brains behind this murder. Meanwhile, Liv and Ravi are surprised to learn that Peyton has returned to Seattle.

While Liv and Clive investigate the murder of a coffee shop owner with an extremely sunny outlook on life, Ravi tests the new cure on a rat before administering it to Major. Meanwhile, Boss discovers who has been moving in on his turf.

When Liv, Clive and Ravi arrive at the scene to investigate a fatal car accident, they begin to suspect foul play was involved. Both starving, Liv and Major consume the brains of the accident victims, a well-meaning father and his angsty teenage daughter. Meanwhile, when Clive is brought in for questioning about a family that was murdered, he’s forced to reveal his past history with them. Lastly, Peyton extends an olive branch to Ravi, and Major hits a road block in his search for Natalie.

When a Dungeon Master is killed, Liv and Clive discover he was up to more than just playing in his mother's basement. Meanwhile, Blaine's experiment does not go as planned. Lastly, Ravi stumbles across some new information that could prove deadly.

Liv consumes the brain of a murdered live-action role-playing knight in order to solve his murder; Peyton uncovers a truth about Liv; Major embarks on a mission.

While Major whisks Liv out of Seattle for her own protection, Ravi eats the brains of a narcissist to help Clive investigate Brother Love for murder.

Liv and Ravi each consume the brain of a very dislikable car salesman and inherit his competitive nature.

As Liv, Ravi and Clive race to finalize the cure, Peyton faces a showdown with Blaine, and Major takes a bold gamble to save Seattle once and for all.