Medical resident Liv Moore becomes a zombie and loses her ambition until she begins working at the city morgue to gain access to brains that give her sustenance and allow her to maintain her humanity. She also learns that her new diet enables her to experience a victim's memories that can be used to help solve the person's murder.

When someone close to Major dies of an apparent suicide, Liv consumes the brains resulting in a mix of reality and paranoia. Clive questions Major and learns of a secret computer file that may contain important details in the investigation – and finding the killer.

Liv consumes the brain of a recently murdered stripper and uncovers some extremely useful information. Meanwhile, Blaine isn’t quite himself lately, and Ravi makes a startling discovery. Lastly, Major and Ravi are helping Peyton move back in with Liv when she receives a surprising phone call.

When Liv consumes the brains of a dominatrix, her bossy and controlling personality makes everyone a little uncomfortable, especially Clive. Meanwhile, Blaine and Peyton have a heart-to-heart.

Liv uncovers the shocking truth about the virus and the far-reaching consequences of the vaccine. Majors exams his future as a human. Blaine makes a business proposal.

Liv and Clive investigate the murder of a pretentious theater actor. Meanwhile, Ravi makes a huge sacrifice for Peyton. Lastly, Blaine makes a startling discovery.

The outside world further isolates Seattle while Peyton, Ravi, Clive and Major race to save Liv from execution for her work as Renegade.

While investigating a murder case with no body and no brain to eat, the only evidence Liv and Clive have to work with is a grainy video and a little bit of blood found at the crime scene. Meanwhile, Blaine is up to his old tricks.

While investigating the death of independently wealthy, 19-year-old, Harris Miller, Liv, on brain à la Ferris Bueller, attempts to cheer up Ravi who has been spiraling after learning some unfortunate news. Meanwhile, after a nasty fall at the crime scene, Clive is forced to continue his part of the investigation via FaceTime. Lastly, things are suddenly going from bad to worse for Blaine.

As Liv, Ravi and Clive race to finalize the cure, Peyton faces a showdown with Blaine, and Major takes a bold gamble to save Seattle once and for all.