A horrific crash sends dozens of soldiers, including Drew's boyfriend, to the emergency room, where TC and Scott clash. Meanwhile, Topher tries to diagnose a soldier's illness, and Kenny tries to improve Ragosa's online-dating profile.

TC and Topher treat the lone survivor of a plane crash while fending off an intimidating law-enforcement officer with a secret motive. Meanwhile, Paul is smitten by an injured exotic dancer whose condition takes a turn for the worse; and Krista cares for a teen with an eating disorder.

An injured skydiver is rescued, but there's more to the case than meets the eye. Meanwhile, the night-shift staffers treat an electrocuted janitor, then scramble to save his wife and children when they fall ill to life-threatening symptoms; and Paul learns about his limitations as a doctor.

As a thick fog descends upon San Antonio, the doctors must improvise to save the victims of a car crash; Topher, Drew and Kenny treat siblings injured in the fog.