April is blindsided by bad news but fights to maintain control over her destiny and to stay strong for her family. She also learns that The Post is cleaning house, but despite her determination to keep her job, extenuating circumstances keep her head on the chopping block. Meanwhile, Brenna learns she is a bone marrow match for an anonymous patient.

April and Leo are in the throes of wedding planning and coming at crossroads when Sara suggests they take a newlywed quiz to help them learn more about each other. Meanwhile, Sara and Beth try to take a night off from dating drama as Brenna finds herself in a big mess with Margo’s crazy ex.

As the wedding date draws near, April is forced to face a list of “lasts,” such as her last week of living at home and her last time being a single girl. While her natural instincts are to have a classy and low-key bachelorette party, Vanessa helps April realize that this might be her last time to live it up. Another possible “last” opportunity presents itself for April when Dominic sets up a meeting for April with his book agent. With her health still in question, this opportunity may be April’s first (and last) chance to get a book published.

April and Leo try their hand at married life, but April worries that Leo has started planning for a future she may not get.

After a shocking traumatic event, April is left reeling and is flung into a world of grief.

April uses her new financial security to do anything and everything she can do feel good again.

Eager to get her book published, April meets with a literary agent who gives her advice she is reluctant to accept. It’s not until she meets a young friend at Camp Hendrie, who helps put things in perspective. But April is not the only one who will need a different point of view. Meanwhile, Brenna opens up about her feelings regarding her father.

Ellie Pratt and April have a long-standing history of rivalry, despite being friends in college. Ready to put this behind her, April is delighted to spend time with Ellie during her visit to Boston - that is, until she discovers why Ellie is there to begin with. Meanwhile, Beth is faced with troubling news that threatens her career and relationship.

Whether it's the Italian honeymoon that never happened, the unchecked item on her bucket list, or her lack of inspiration, all signs point April to Rome. Caught up in the midst of family drama, April faces too many distractions that keep her from making progress on her book. But will April find the inspiration she seeks in Rome, or will this trip lead her down another path? Meanwhile, Brenna receives devastating news from Finn.