April tries to impress her boss and gets involved in an office romance. She then receives a unexpected diagnosis, when she finds out she has cancer.

When Beth hosts a house party, April lets loose – a little too loose – which leads to a major blowout with her friend. The new school year finds Brenna feeling alone and bullied. Meanwhile, Leo gets some valuable advice from Sara and ends up getting a job, but he finds the new experience more challenging than he expected.

April gets some welcome news from Dr. Hamburg that bodes well for both her and Leo. At work, she gets wind of a possible story opportunity with baseball player Richie Miranda, but when she gets a bigger scoop than she bargained for, she is faced with a tough moral choice.