With the meta-human cure ready to use, Barry and Team Flash must figure out a way to subdue Cicada long enough to take it. Killer Frost steps in to help with the plan. Meanwhile, Joe eases back into work, and Nora isn’t happy about the way her dad plans to stop Cicada.

Team Flash finds out that a suburban mom named Vickie Bolen is in danger and they race to save her. Upon meeting her, they discover she’s a meta-human who is hiding her abilities from her family. Barry encourages Vickie to share her secret with her family, which makes Nora realize she needs to come clean with her parents about Thawne.

When Icicle returns to enact the next phase of his devious plan, Caitlin and her mother, Dr. Carla Tannhauser, must resolve their long-combative relationship to defeat the icy monster. After Barry makes a big decision about their family without consulting her, Iris decides to take matters into her own hands.

Barry continues to struggle with how he feels about Nora's betrayal. Brie Larvan, Joss Jackam and Peter Merkel return to Central City. Meanwhile, Cisco makes a bold decision.

Team Flash is on high alert after Cicada II threatens to unleash a dangerous virus that would put all meta-humans at risk.

Barry faces off with his oldest, and most formidable nemesis, Reverse Flash.