When aliens called the Dominators attack Central City, Barry speeds over to Star City to ask the Green Arrow for help in stopping them. Realizing the battle against the Dominators is bigger than they thought, they track down the Legends of Tomorrow, and Barry and Cisco create a breach to bring back a secret weapon – Supergirl. Once all of the super friends are assembled, they come up with a plan to attack but a shocking secret related to Flashpoint is revealed and suddenly no one is sure who they can trust. Meanwhile, Wally wants to join the battle against the aliens but Iris tells him he’s not ready.

The crossover starts on Supergirl S02E08 Medusa (I). It continues on Arrow S05E08 Invasion! (III) and DC's Legends of Tomorrow S02E07 Invasion! (IV).

Barry and team are surprised when Mon-El and Hank Henshaw arrive on their Earth carrying a comatose Supergirl who was whammied by the Music Meister. Unable to wake her up, they turn to Team Flash to save her. However, the Music Meister surprises The Flash and puts him in a similar coma, one that Team Flash can't cure. Kara and Barry wake up without their powers in an alternate reality where life is like a musical and the only way to escape is by following the script, complete with singing and dancing, to the end.

The crossover starts on Supergirl S02E16 Star-Crossed (I).

When Barry Allen and Oliver Queen wake up one morning and realize they have swapped bodies with each other, the two set off to find out what disturbed the timeline to cause such a shift. However, things quickly go from bad to worse when they present their case to Team Flash and the gang doesn’t believe them. Barry and Oliver realize they need Supergirl’s help and travel to Smallville on Earth-38 where they end up meeting Kara’s cousin, Clark Kent, and intrepid reporter, Lois Lane.

The crossover continues on Arrow S07E09 Elseworlds (II) and Supergirl S04E09 Elseworlds (III).

Pariah enlists Black Lightning to help stop the Anti-Monitor after Flash-90 shares what he learned from his battle in ‘Elseworlds.’ With the help of Black Lightning, Barry, Cisco and Killer Frost come up with a plan that could save them all. Meanwhile, Iris has a heart-to-heart with Ryan Choi, while Oliver and Diggle return to an old familiar stomping ground.

The crossover starts on Supergirl S05E09 and Batwoman S01E09. It continues on Arrow S08E08 and Legends of Tomorrow S05E01.