RYAN SEACREST is here to talk about the twists for the new season of ""American Idol."" Teenage pop sensation JOJO drops by to perform her new single, ""Baby It's You"" and her #1 hit, ""Leave (Get Out)."" Plus, a house call from the ""Desperate Housewives'"" favorite plumber, JAMES DENTON!

RAY ROMANO gives us a peek at his adolescent years and his twin boys show off their acting talents! From ""Desperate Housewives,"" actor JAMES DENTON talks about the recent rumors from the set. And, you'll be amazed by five-year-old anatomy expert, MATTHEW SAWCHUK.

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