As Victor struggles to resurrect Brona, Ethan prepares to leave London and Malcolm discovers that Vanessa is plagued by new visions.

Vanessa meets Caliban for the first time, while Victor begins to train the resurrected Brona in the rudiments of language. Meanwhile, the group turns to Ferdinand for help translating the Verbis Diablo.

While Ferdinand helps Malcolm decipher Brother Gregory's writings, Vanessa helps Victor pick a dress for his cousin. Meanwhile, Dorian takes Angelique on a date, and Ethan rescues a young woman from a runaway horse.

After sealing the townhouse against further intrusion, the group goes its separate ways for the moment. Rusk starts asking questions of Ethan, Brona and Victor draw closer, Vanessa teaches Caliban how to dance, and Evelyn launches her next steps in her campaign to seduce Malcolm.

Malcolm fights off Evelyn's enchantment and goes to confront her. Meanwhile, Brona reveals her true colors to the Creature, and Angelique finds Dorian's portrait.

While Evelyn torments Malcolm, Victor summons Ethan and Vanessa back to London to rescue their friend. Meanwhile, Brona learns Dorian's secret, and Caliban is betrayed.

Vanessa has to use all of her strength to try and defeat the demon.

Ethan, now a prisoner under the watchful eye of Scotland Yard Inspector Rusk, is on a train speeding through the desert of the American West. Meanwhile, Sir Malcolm is confronted by a mysterious Native American man in Zanzibar. Back in London, Dr. Frankenstein seeks out his old friend Dr. Jekyll and Vanessa seeks the help of Dr. Seward to battle a new evil.

Lily and Dorian pay a visit to a most unusual show, and Vanessa invites Sweet to a different show. Rusk sets out to track down Ethan and make sure that he hangs, and Henry demonstrates the efficacy of his potion for Victor.

Vanessa asks Seward to hypnotically regress her after learning that she met the Master sometime in the past. Rusk learns that Ethan has a new ally. Caliban finds his wife and child. Lily and Dorian have Justine pledge her service to them.

Hecate and Ethan try to survive in the desert wasteland, as thirst and their unrelenting pursuers take their toll. Meanwhile, Victor and Henry continue with their work in Bedlam.