Roy and John buy an old fire engine, and Station 51 gets a new engine. A woman overdoses on LSD and Roy tries to talk her down, leading the two paramedics on a chase to the top of a building. Brackett treats a resilient gunshot victim. A politician suffers a heart attack and the station responds to a warehouse fire.

Tired of Chet's antics, the guys at the station get their revenge by playing practical jokes of their own. A gun discharges by accident and injures a pregnant woman, a construction worker caught under a boat refuses an IV, and a man in a motorcycle accident communicates through his thumb.

A young OD victim is brought into the ER. A man fakes back pain to get a free ride to the hospital. John gets peeved at all the frivolous calls the squad goes on while real emergency victims need help. A man is shocked after kicking in his TV screen. The ambulance carrying the paramedics and a heart attack victim is involved in a traffic accident.