Red believes he knows who was responsible for a prominent prosecutor's 12 year disappearance; Red investigates the woman who tempts Tom.

When Red tips Liz off about the disappearance of a polygamous cult leader with dangerous shipping containers buried on his property, the task force sets out to investigate. Red utilizes his sources to appease Fitch’s last words and tries to track down his hidden safe.

A former paramour involves Reddington in a deadly game with a wealthy, powerful family dynasty whose ill-begotten fortune was amassed from an underground auction of human and material contraband. Meanwhile, Tom takes on a new mission.

Evidence mounts against Liz in a murder case, triggering Red and Ressler's efforts to clear her name by tracking down the recently vanished Tom Keen.

The task force tracks a scientist who abducts disabled patients to conduct experiments on immortality. Now back in Washington, DC, Tom scrambles to save himself from new enemies.

Red fights for his life while the task force races to track down a mysterious figure from his past while Tom provides help in an unexpected way.

After decoding the information that is embedded in The Fulcrum, Red is determined to stop the imminent threat. Meanwhile, the task force discovers that deceased bodies of Chinese-American women are being smuggled out of the country under false identities. Liz continues to search for answers about her past after discovering a picture hidden in Red's secret flat.

Following intel from Red, the FBI find themselves one-step behind the most dangerous Russian Assassin, Karakurt, an enemy on U.S. soil. To avoid catastrophe, Liz and Ressler meet with Russian Counter-Intelligence who offer insight not only on Karakurt, but also on the identity of Liz’s mother. Cooper finds himself in a compromising position.

Liz realizes she is being framed by The Cabal forcing Red to use his connections to help her clear her name. As Cooper receives shocking news, Ressler, Samar, and Aram must decide who on the task force can still be trusted.