Liz and Red take a detour to the Midwest. Ressler, Aram and Samar accidentally uncover what could turn into a global food crisis. Cooper seeks help from an unexpected source.

As Red sets Liz and the Task Force on the trail of an eco-terrorist with a mysterious connection to Alexander Kirk, Tom takes matters into his own hands.

After being dosed with poison, Red must retrace his steps to discover which of his closest allies has betrayed him, while the task force races against the clock to find an antidote that will save him.

After weeks of hunting for Dembe, Red and the Task Force finally get a lead on his whereabouts when Aram goes missing. Meanwhile, Dembe takes a calculated risk as Red closes in

While the Task Force investigates a series of suspicious police shootings, Agent Ressler is distracted by increasing external pressures. With his back up against the wall, Red drafts Tom in executing an elaborate plan to help re-establish his criminal reputation.

When Red goes on the hunt for a legendary treasure, he draws the attention of Abraham Stern, a cunning manipulator who has devoted his life - and the lives of many innocents - to recovering the fortune that is his birthright. Meanwhile, Liz's quest sends her down a dark path, leading her to study the methods of one of the Blacklist's most dangerous criminals.

Desperate for information about the whereabouts of a longtime friend, Red directs the Task Force to find a blacklister who specializes in untraceable money transfers. Meanwhile, Liz receives some disturbing news from her daughter Agnes.