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Ozzy & Drix, also known as The Fantastic Voyage Adventures of Osmosis Jones & Drixenol and Osmosis Jones: The Animated Series, is an American animated television series based on the Warner Bros. film Osmosis Jones and it was produced by Warner Bros. Animation. It takes place inside the body of teenager Hector Cruz. The series premiered on September 14, 2002 on the Kids' WB; the final episode aired July 5, 2004. Unlike the original movie it spun off from, Ozzy & Drix was entirely animated and contained no live action. It stars Phil LaMarr as the replacement for Chris Rock as Osmosis Jones, and Jeff Bennett as the replacement for David Hyde Pierce as Drix. As of July 2011, episodes of the series are still available via the Kids WB website. The show also aired on Teletoon in Canada. The show is also slightly less violent than the movie, having the characters treated like people rather than simply cells, and having none of them killed off, unlike the movie where Thrax managed to kill off several cells. There are also new characters that replace the ones from the original movie such as Maria Amino replacing Leah Estrogen, Mayor Spryman replacing Mayor Phlegmming, Sylvian Fischer replacing Tom Colonic, Chief Gluteus replacing The Chief of Police, The Mole replacing Chill the Flu Shot and Scarlet Fever replacing Thrax.

Series Cast

  1. Phil LaMarr as Osmosis Jones (voice)

    Phil LaMarr

    Osmosis Jones (voice)

    26 Episodes

  2. Jeff Bennett as Drix (voice)

    Jeff Bennett

    Drix (voice)

    26 Episodes

  3. Alanna Ubach as Mayor Paul Spryman / Hector's Mom (voice)

    Alanna Ubach

    Mayor Paul Spryman / Hector's Mom (voice)

    26 Episodes

  4. Justin Cowden

    Hector Cruz (voice)

    26 Episodes

  5. Tasia Valenza as Maria Amino (voice)

    Tasia Valenza

    Maria Amino (voice)

    26 Episodes

  6. Jim Cummings as Police Chief Gluteus (voice)

    Jim Cummings

    Police Chief Gluteus (voice)

    26 Episodes

  7. Rob Paulsen as Travis Lum (voice), Stickety Lipid (voice), and Backseat / Travis Lum (voice)

    Rob Paulsen

    Travis Lum (voice), Stickety Lipid (voice), Backseat / Travis Lum (voice)

    12 Episodes

  8. Vivica A. Fox as Ellen Patella (voice)

    Vivica A. Fox

    Ellen Patella (voice)

    6 Episodes

  9. Pat Fraley as Pnuemoniac (voice), Brain Advisor #1 (voice), and Nerve Cell General (voice)

    Pat Fraley

    Pnuemoniac (voice), Brain Advisor #1 (voice), Nerve Cell General (voice)

    5 Episodes

  10. View More

Full Cast & Crew

Last Season

Season 2

2003 | 13 Episodes

Season 2 of Ozzy & Drix premiered on August 23, 2003.

View All Seasons

Ozzy & Drix
Ozzy & Drix


Status Ended


  • See more TV shows from The WB...

Type Scripted

Original Language English


Content Score


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