The people of Chester's Mill panicked state when a meningitis outbreak hits the community, threatening the already scarce supply of drugs. Meanwhile, Julia continues to seek answers to her husband's disappearance

When the town begins to run low on water, the residents of Chester's Mill begin to fight for the remaining resources. Meanwhile, Julia discovers a strange connection that two of the town's residents have with the Dome.

Julia uncovers the truth about her husband's disappearance and unravels some of Chester's Mill's darkest secrets. Meanwhile, Maxine shows Barbie how she plans to take control of the town.

Big Jim turns the town against Barbie when the truth about his past is revealed. Meanwhile, Maxine makes it personal when she confronts Barbie’s closest ally.

While the manhunt for Barbie continues, Big Jim gets the residents of Chester’s Mill riled up and the town demands justice for all of Barbie’s supposed crimes. Meanwhile, Joe and Norrie must find a new hiding place for the mini dome.