Having noticed a slight change in the photo of his fiancé and him, Jin wonders if saving Ryoma has altered the future. He decides to try to stay out of events in the village to prevent anymore changes. However, as cholera sweeps the village, the medicine men call upon Jin to give them the cure. He tells them that he does not know. As hard as he tries to stay neutral, Jin's decision is challenged when Kiichi, the son of the woman he saved, becomes ill. Saki confronts him, as he asks her to return to her home. However, his fondness for the boy, changes his mind.

Now that Jin has Koan Ogata, the supervisor of the Western Medicinal Office for the village, and his team on his side, Jin begins to create a large-scale plan. He asks if rubber hoses exist and if a syringe needle can be made to create an IV drip. The town begins to make saline solution, sterilize everything with alcohol, and burying waste and burnt clothes in large ditches. Ryoma takes it upon himself to be the leader of waste disposal. Jin teaches the doctors how to administer an IV drip. Kiichi and Yamada recover. Jin suddenly becomes sick and has delusions while ...

It is now winter of 1862. Jin had confessed to Saki that he is from the future. However, she has gone about as if nothing has happened. Kiichi is an apprentice at Daikichi's shop. Ryoma has become Katsu's student, while Kyotaro is his secretary. Jin is lecturing at the Western Medical office, with Saki in attendance and Ogata as his most fervent and out-spoken student. One day, as Jin is creating a tool that could drill a hole in a patient's skull, he and Saki get too close. She jumps away and asks him what he wants for dinner. She agrees to make him a special dish.

After the check-up with Oyoji, Courtesan Nokaze asks Jin to see another patient. He discovers a former courtesan in the last stages of syphilis. There is no cure, since penicillin has not yet been discovered. Jon tries to persuade the rest of the prostitutes at the brothel to accept to an examination for signs of syphilis. However, they call him a pervert and refuse. Feeling defeated for his inability to help Courtesan Nokaze, Jin suddenly recalls the first meeting with Miki. She presented him with the procedure to create penicillin. He immediately seeks the help of ...

With Jin's growing popularity, the Study of Medicine Office find him a threat to their livelihood and status as the medical authority. A surgical instrument of Saburi's is found in the room of a murdered prostitute. The doctors at the Study of Medicine Office use it to their advantage to accuse Saburi of murder. He confesses that he's had an agreement to do autopsies at the Yoshiwara in exchange for a proper burial for the prostitutes. Ogata takes responsibility and resigns. However, Jin decides it would be best if he resigned instead to keep Ogata as head of the ...

It is 1863. Jin recognizes that it is the beginning of the Bakumatsu period. Ryoma, (a prominent historical figure who fights for the creation of a modern government, to prevent colonization), has been sent to build a strong navy. Kiichi's mother, Tae, is severely burnt by hot oil. Jin is summoned and prepares to do a skin graft. He asks Ogata for lots of penicillin to prevent infection. Since the factory was destroyed, Yamada has been in charge of restarting the production. Ogata invites a friend, Hamaguchi, to observe the surgery. As the surgery is about to end, ...

Kyotaru sells his late father's treasured tea cups to buy a pair of glasses for Hatsune, a prostitute he first met while guarding Jin at Yoshiwara. With Ogata dead, Jin must prove his worthiness for Hamaguchi to fund making a more potent penicillin. Jin goes to Yoshiwara to see another ill prostitute, Hatsune. A local doctor performed an abortion that caused blood-poisoning. The penicillin is not potent enough. They must try to find immediate funding for a new production a much more potent dose. A male actor, who plays theatrical female roles, is asked to loan the ...

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We don't have an overview translated in English. Help us expand our database by adding one.