After Xena's death, Gabrielle becomes Queen of the Amazons, while Autolycus finds himself possessed by the warrior princess, Xena who needs ambrosia to bring herself back to life. But Xena's rebirth and Gabrielle's life are both threatened by an Amazon bent on obtaining the Amazon crown and the ambrosia.

Xena, Gabrielle and the Amazons must battle an evil Amazon, who ate ambrosia and is now a god. She wants Gabrielle dead and in order to stop her, Xena and Gabrielle resort to asking for the help of the now immortal Callisto.